Patient should be given Hydralazine
, Labetalol and Nitroglycerin.
The most commonly used intravenous medications for this purpose are labetalol and hydralazine
. Other medications can include oral rapid-acting nifedipine.
As per inclusion and exclusion criteria, patients with chronic heart failure on follow-up who were started on Hydralazine
plus nitrates were assigned to the study and were compared with the same number of patients who were not on hydralazine
Subjects who met the 2012 Chapel Hill Classification criteria for granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) (9) and were on hydralazine
therapy prior to diagnosis of AAV were identified as having hydralazine-induced vasculitis.
The patient had been taking several blood pressure medications including hydralazine
at a dose of 50 mg TID.
If labetalol is not available, we use hydralazine
administered as a 10-mg IV bolus over 2 min.
All patients were taking hydralazine
and oral ferrous sulfate.
Key Words: Gas chromatography, Hydralazine
, Ethyl chloroformate, Derivatization, Blood serum, Urine.
Cautious weaning led to discharge on carvedilol and enalapril (and cessation of hydralazine
The main drugs that are known to cause this include minocycline, alpha methyldopa, nitrofurantoin, diclofenac, hydralazine
, statins, and anti-TNF agents .
Of the dozens of agents known to cause DIL, procainamide and hydralazine
remain the most common, with an incidence of 20% for procainamide and 5-8% for hydralazine
induced lupus syndrome (HILS) was first reported in 1953.