hydrolase


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Related to hydrolase: oxidoreductase, transferase

hydrolase

[′hī·drə‚lās]
(biochemistry)
Any of a class of enzymes which catalyze the hydrolysis of proteins, nucleic acids, starch, fats, phosphate esters, and other macromolecular substances.
References in periodicals archive ?
Soluble epoxide hydrolase (sEH), a member of the epoxide hydrolase family, is found mostly in cytosol but also in the peroxisomes of some mammalian tissues including liver, kidney, intestine and vascular tissues (Morisseau and Hammock 2013).
brasiliensis which shows almost 60 % homology in its amino acid sequence to the patatin from potato tuber also exhibits a nonspecific lipid acyl hydrolase activity [3] that catalyze the cleavage of fatty acids from membrane lipids including phospholipids, lysophospholipids, galactolipids, and mono and diacylglycerols.
Novel hydrolase diversity retrieved from a metagenome library of bovine rumen microflora.
Pinto et al (18) have demonstrated that PSMA has folate hydrolase activity, and others have shown a neuropeptidase function.
However, unlike Gram-negatives, the Gram-positive bacteria possess a single gene rel, which codes for an enzyme Rel having both (p)ppGpp synthetase as well as hydrolase activity.
Enzymatic hydrolysis of organophosphates: cloning and expression of a parathion hydrolase gene from Pseudomonas diminuta .
2] Human genes: BRCA1, breast cancer 1, early onset; BRCA2, breast cancer 2, early onset; MGST3, microsomal glutathione S-transferase 3; GBP1, guanylate binding protein 1, interferon-inducible, 67kDa; MTAP, methylthioadenosine phosphorylase; GGH, gamma-glutamyl hydrolase (conjugase, folylpolygamma-glutamyl hydrolase); MADCAM1, mucosal vascular addressin cell adhesion molecule 1; POSTN, periostin, osteoblast specific factor; PMS1, PMS1 postmeiotic segregation increased 1 (S.
Infinity's programs in the inhibition of the Hsp90 chaperone system, the Hedgehog pathway and fatty acid amide hydrolase are evidence of its innovative approach to drug discovery and development.
2006) identified serine hydrolase KIAA1363 that is diethyl phosphorylated in mouse brain by chlorpyrifos oxon.
Alliance For Sustainable Energy, LLC (Golden, CO) has patented purified cellobiohydrolase I (glycosyl hydrolase family 7 (Cel7A) enzymes from Penicillium funiculosum which demonstrate a high level of specific performance in comparison to other Cel7 family member enzymes when formulated with purified EIcd endoglucanase from A.
In this trial, tumour expression of TS, DPD and gamma-glutamyl hydrolase, related to antifolate resistance [7], did not condition RR in both arms.
Brandstadt, Lane, and Gross solve this problem with enzyme catalysts such as hydrolase enzymes.