hydroxylation reaction

hydroxylation reaction

[hī‚dräk·sə′lā·shən rē‚ak·shən]
(organic chemistry)
One of several types of reactions used to introduce one or more hydroxyl groups into organic compounds; an oxidation reaction as opposed to hydrolysis.
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Joshi, Influence of Preparation Parameters on Characteristics of Zirconia- Pillared Clay Using Ultrasonic Technique and Its Catalytic Performance in Phenol Hydroxylation Reaction, Kor.
(25) In the reaction, 1 atom of molecular oxygen is transferred to the substrate and the other one is reduced to water by 1 mole of NADPH, and molecular oxygen is activated for the hydroxylation reaction.
The present study sought to develop an efficient conversion of substituted arylboronic acids to substituted phenols by an oxidative hydroxylation reaction using [(N[H.sub.4]).sub.2][S.sub.2][O.sub.8] under metal-, ligand-, and base-free conditions.
These multiple carbon-carbon double bonds are also capable to be reacted to introduce hydroxyl groups through a hydroxylation reaction.
As the subsequent hydroxylation reaction progressed, it was observed that the epoxide peak gradually diminished while a hydroxyl band at approximately 3444 [cm.sup.-1] became increasingly prominent [14].
It is shown here that, unlike the complete hydroxylation reaction, the uncoupled decarboxylation reaction involves stoichiometric ascorbate consumption.
Hydrogen peroxide (30 wt%) and formic acid (88 wt%) from Laboratorios Cicarelli were used in the hydroxylation reaction. Triethanolamine (>99%) from Laboratories Cicarelli and lithium hydroxide (>99%) from Fluka were used in the alcoholysis reaction.
In the course of the hydroxylation reaction, the enzyme-bound Fe(II) splits dioxygen into two atoms, being converted itself to Fe(III) or Fe(IV).
Vitamin C is necessary for multiple hydroxylation reactions, including hydroxylation of proline and lysine in collagen synthesis, beta-hydroxybutyric acid in carnitine synthesis, and dopamine-beta-hydroxylase in catecholamine synthesis.
[2] The vitamins D2 and D3 are not biologically active, but are converted in vivo to the active form of the D vitamin by two sequential hydroxylation reactions.
These variants were near genes involved in cholesterol synthesis, hydroxylation reactions, and vitamin D transport.
It is biologically inert and has to undergo two hydroxylation reactions to become active in the body.