hydroxyurea


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hydroxyurea

[‚hī¦dräk·sē·yu̇′rē·ə]
(pharmacology)
HONHCONH2 Needlelike crystals with a melting point of 133-136°C; used as an antineoplastic agent. Also known as hydroxycarbamide.
References in periodicals archive ?
The children so identified, are placed on monthly transfusions or daily oral hydroxyurea especially in situations where safe blood is not readily available as a means of stroke prevention.
Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia.
She had been on hydroxyurea only one year before confirmation of pregnancy and then stopped.
Published analytical techniques for the measurement of hydroxyurea in biological fluids include colorimetric spectrophotometry (10,11), HPLC (12-15), and mass spectrometry (MS) (16, 17).
The GDN earlier reported that more than 40 per cent of sufferers being cared for at the Genetic Blood Disease Centre in SMC are now taking hydroxyurea that was first made widely available in Bahrain last year.
He was initially well controlled on the standard hydroxyurea treatment.
used hydroxyurea, a chemotherapeutic agent which induces Hb F production, at a dose of 10 mg/kg, in their patients assuming that since pathophysiology of Hb SD-Punjab is similar to Hb SS, increasing the level of Hb F might decrease the vaso- occlusive events.
Studies proved the efficacy of hydroxyurea medication in reducing the number of bouts of pain.
sup][1] Hydroxyurea is another reportedfirst-line agent, and combined medication of hydroxyurea and corticosteroid increases the response rate.
has earned a $25 million milestone payment from Novartis, triggered by the EMA's positive opinion for Jakavi (ruxolitinib) for the treatment of adult patients with polycythemia vera (PV) who are resistant to or intolerant of hydroxyurea.
The "much anticipated" guideline to help primary care and emergency clinicians improve the management of sickle cell disease includes a consensus treatment protocol for implementing hydroxyurea therapy and more detailed guidance regarding longterm transfusion therapy, according to a summary report published in Journal of the American Medical Association.