hyperchromatic


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hyperchromatic

[¦hī·pər·krō′mad·ik]
(biology)
Staining more intensely than normal.
References in periodicals archive ?
(B) Cells have moderate amount of basophilic cytoplasm with eccentrically located, round to oval hyperchromatic nucleus (Leishman stain; X400)
These cells have a high nuclear to cytoplasmic ratio and round to oval hyperchromatic nuclei, with irregular nuclear membrane, fine to coarsely clumped chromatin, single to multiple nucleoli, and a small amount of pale cytoplasm.
Histopathological examination showed a highly cellular cerebellar tumor consisting of sheets of uniform cells with a high nuclear/cytoplasmic ratio and round to oval hyperchromatic nuclei.
(b) 630x Romanowsky stain demonstrating vessel and plump hyperchromatic nuclei and intracytoplasmic lumen (arrow).
They contain the architectures of both traditional GBM and PNET-like areas, with hypercellularity, minimal fibrillary background, high nuclear-tocytoplasmic ratio, oval-round hyperchromatic nuclei, high mitotic-karryorhectic indices, and Homer Wright neuroblastic rosettes.
In our case, the tumor presented spindle tumor cells, with hyperchromatic nuclei, exhibiting moderate to severe atypia, but without any particular histologic phenotype, as the above mentioned variants represent rare entities [3; 6].
Caption: Figure 2: (a) Cytology of the nodules showing anisokaryosis, hyperchromatic and stippled nuclei, prominent nucleoli, intranuclear inclusions, and pigment laden macrophages (H and E; x 100), (b) histopathology showing pleomorphic tumor cells with pleomorphic round to oval nuclei, prominent eosinophillic nucleoli, multinucleate giant cells with intracytoplasmic melanin pigment and atypical mitotic figures (H&E; X100).
Microscopic examination revealed replacement of ovarian architecture by tumor cells containing enlarged, hyperchromatic, irregular nuclei arranged in sheets punctuated by microcystic spaces, not unlike the reticular variant of yolk sac tumor (YST) [Figure 1]c.
The nuclei are hyperchromatic and mildly pleomorphic with some showing prominent nucleoli (Figure 4).
Microscopy showed sheets of medium to large lymphoid cells with hyperchromatic nuclei and scanty cytoplasm (Figures 2(a)-2(d)).
The light microscopic examination revealed squamous cell carcinoma (SCC) as acanthotic squamous epithelium with deep rete pegs, epithelial and keratin pearls, pleomorphism, stromal infiltration and hyperchromatic nuclei (Fig.
Whereas adult GCTs comprise diffuse cords or trabeculae and small follicles termed Call-Exner bodies of rounded cells with scant cytoplasm and pale "coffee-bean" nuclei, juvenile GCTs have nuclei that are rounded, hyperchromatic with moderate to abundant eosinophilic or vacuolated cytoplasm.