in lymphosarcoma in a cockatiel (Nymphieus hollandicus) and a blue and gold macaw (Ara ararauna).
1-14) The pathogeneses of SLE and SS are similar, suggesting that aberrations in T and B cells could lead to polyclonal B cell hyperactivity, hyperglobulinemia
, and autoantibody production.
Incipient myelomatosis or 'essential' hyperglobulinemia
with fibrinogenopenia: a new syndrome?
Approximately 50% of patients with the plasma cell variant experience systemic manifestations, including fever, anemia, and hyperglobulinemia
The hyperprotidemie and hyperglobulinemia
resulting from the hyper-[gamma] globulin.
The occurrence of either high titer RF, hyperglobulinemia
or a small monoclonal peak support a possible diagnosis of primary Sjogren's syndrome, which should be actively sought by history, ocular examination, and antibody screening.
Diagnosis of syndromes associated with hyperglobulinemia
may spuriously elevate measured serum inorganic phosphate levels.
Laboratory abnormalities included anemia, hypercreatinemia, an elevated aspartate aminotransferase level, and hyperglobulinemia
Previous reports suggest an autoimmune process characterized by hyperglobulinemia
and non-organ-specific autoantibodies.
29-31) This included a combination of 3 or more of the following clinicopathologic results consistent with mycobacteriosis in doves (28-31): positive results of Western blot analysis, anemia, leukocytosis, heterophilia, monocytosis, hyperglobulinemia
, and hypoalbuminemia.
Should ANCA develop later, there would still be unresolved questions: hyperglobulinemia
and enlarged kidneys in the face of renal failure with no evidence of HIV, multiple myeloma, or amyloidosis.