hyperimmune serum


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hyperimmune serum

[¦hī·pər·ə′myün ′sir·əm]
(immunology)
An antiserum that provides a very high degree of immunity due to a high antibody titer.
References in periodicals archive ?
To this end, two Inhibition ELISA methods (IEM), using the mAbs or hyperimmune serum, were developed to determine total anti-CHIKV antibodies.
The antigen in the working dilution was added through the central hole and hyperimmune serum was added at different dilutions through the peripheral holes.
Hyperimmune serum collected 21 weeks after the primary immunization of the rabbits was used in a checkerboard titration with the diminazene-enzyme conjugate to determine their optimum dilutions.
The hyperimmune serum specificity was tested by antigenic erythrocyte diagnosticums: plague, pasteurellosis, pseudotuberculosis, Leptospira.
The hyperimmune serum (1 ml, 256 IHA units) injected intravenously and intramuscularly to PM-challenged rabbits showed 100% protection and 66.
Immunohistopathological studies: Hyperimmune serum was raised against ND virus in rabbits (Samiullah et al.
Hyperimmune serum samples raised against the isolated bacteria neutralized the CPE of the bacteria up to a 1:719 dilution.
Slide agglutination with type-specific hyperimmune serum and specific multiplex PCR (8,9) identified the isolate as serotype 2.
Consistent with this assumption, a rat hyperimmune serum specimen, raised against a truncated recombinant rat HEV CP derivative, reacted strongly with the homologous antigen but weakly with genotype 3 HEV antigen (P.
Hyperimmune serum samples were established by using a 4-fold vaccination of pigs with antigens of H1N1 vaccine strains (A/New Jersey/8/1976, A/sw/Netherlands/25/1980, A/sw/IDT/Re230/1992, A/sw/Haselunne/IDT2617/2003), and a strain of pandemic (H1N1) 2009 virus (A/Hamburg/7/2009) by using Freund adjuvant.
Homologous hyperimmune serum specimens were produced in BALB/c mice as previously described (8).
To develop the WU ELISA and the KI ELISA, we used as positive controls 2 convalescent serum samples from a child known to be infected with WUPyV and rabbit hyperimmune serum for WUPyV VP1 or KIPyV VP1, and we used as negative controls rabbit preimmune serum and serum derived from pediatric patients ([less than or equal to] 3 years of age).