hyperleptinemia


Also found in: Medical.

hyperleptinemia

[‚hī·pər‚lep·tə′nē·mē·ə]
(medicine)
Increased serum leptin level.
References in periodicals archive ?
Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction.
Deranged lipid metabolism, activation of the RAS, and hyperleptinemia lead to the development of hypertension10.
In rats given a high-fat diet, those exposed to BPA had a greater increase in obesity, dyslipidemia, and hyperglycemia (some of the conditions that define metabolic syndrome in humans), as well as in hyperleptinemia, hyperinsulinemia, and glucose intolerance, than unexposed rats on the same diet (Wei et al.
Hyperleptinemia directly affects testicular maturation at different sexual stages in mice, and suppressor of cytokine signaling 3 is involved in this process.
Association between hyperleptinemia and oxidative stress in obese diabetic subjects.
In the same study chronically induced hyperleptinemia was shown to induce resistance to natriuresis and NO like effects.
The main group was characterized with hyperleptinemia and increased levels of VEGF and resistin, which correlated with an increase in MAU and a decline in GFR.
Protodioscin ameliorated dyslipidaemia, insulin resistance, hyperleptinemia and hyperuricaemia in high fructose fed mice
Hyperleptinemia and hypoadiponectinemia have been associated with increased risk of insulin resistance, overweight, and diabetes mellitus in adult patient [11].
Finally, the diabetic mice we used (db/db) suffer from obesity and hyperleptinemia, and these factors may have effects on endothelial function independent of diabetes per se.
28) Normal leptin Characteristics values Hyperleptinemia 45 8 Mean age [+ or -] SD (a), years 28 [+ or -] 11 19.