Infantile cortical hyperostosis
and COL1A1 mutation in four generations.
HHS is characterized by painful diaphyseal hyperostosis
and may overlap with the TC phenotype in some cases.
Dysphagia, paralysis in vocal folds, compression to inferior vena cava, and neurological compression syndromes have been reported in patients with extreme hyperostosis
. There may be spinal fractures with weak trauma causing neurological problems.
Failed videolaryngo-scope intubation in a patient with diffuse idiopathic skeletal hyperostosis
and spinal cord injury.
In children, OO may be mimicking different diseases such as infantile cortical hyperostosis
, osteomyelitis, Perthes disease, leg length discrepancy, healing stress fractures, tuberculosis, neuromuscular conditions, as well as malignant tumors (osteosarcoma, Ewing sarcoma) .
CT images (C), show well circumscribed densely calcified dural-based lesion associated with buckling of adjacent cerebral cortex, irregularity along the adjacent inner table of right parietal bone and reactive hyperostosis
. No cranial vault invasion was seen.
Radiologically, it is characterized by the presence of hyperostosis
foci at any point in the skeleton, and associated with numerous disorders including Buschke-Ollendorff syndrome, rheumatoid arthritis, scleroderma, ankylosing spondylitis, synovial osteochondromatosis, Klippel-Feil syndrome, cleft palate, Familial Mediterranean fever, endocrine diseases, syndactyly, and melorheostosis.
Bony manifestations include cystic lesions, hyperostosis
of the inner table of the calvaria, osteoblastic changes, periosteal new bone and scoliosis.
Significantly, urbanisation is also associated with the first evidence of diffuse idiopathic skeletal hyperostosis
(DISH), widely seen as a proxy for obesity.
Computed tomography (CT) was performed and a non-specific soft tissue mass filling the middle ear and mastoid cavities, associated with a hyperostosis
of the temporal bone and a hairy aspect of the margins of this hyperostotic boney reaction, was seen on the right side (Figure 1).
In the literature they are also designated as hyperostosis
, exostosis and osteomas.1 Tori are self-limiting and painless, but they may grow over several centimeters and then contribute to periodontal disease of adjacent teeth by forcing food during chewing toward the teeth instead of away from them.