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Condition caused by increased functioning of the parathyroid glands.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a disease caused by excessive production of the hormone of the parathyroid glands, usually occurring as the result of adenoma of those glands.

An excess of parathyroid hormone mobilizes the calcium in the bones, raises its level in the blood and lowers the level of phosphorus, and raises the quantity of calcium and phosphorus in the urine (which is then discharged). Softening and deformation of the bones is the result of this process, making possible spontaneous fracture or fracture caused by minimal injury. Visceropathic forms of hyperparathyroidism are characterized by calcium deposits in the internal organs. The most widespread is the renal form (formation of calculi in the kidneys and urinary tracts). The cause of formation of adenomas in the parathyroid glands is not known. Hyperparathyroidism is more commonly found in women. Treatment involves removal of the tumor; orthopedic treatment is necessary when the disease affects the bones, and removal of the calculi is necessary in nephrolithiasis.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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Its meaning is of clinical importance since it can be a cause of persistent hyperparathyroidism. Their number can vary between 5 and 11 as described by Akersrom in his series of 503 autopsies [7].
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In one of the families, renal lesions were even more prominent, as five out of six individuals had renal lesions, while hyperparathyroidism was found in four individuals and jaw tumor was found in two individuals only [21].