Hypersomnia

(redirected from hypersomnolence)
Also found in: Dictionary, Thesaurus, Medical.

hypersomnia

[‚hī·pər′säm·nē·ə]
(medicine)
Excessive sleepiness.

Hypersomnia

 

increased sleepiness. A distinction is drawn between paroxysmal and permanent types of hypersomnia. Characteristic of paroxysmal hypersomnia are overwhelming attacks of sleep during the day, under unfavorable conditions lasting from several minutes (narcolepsy) to several days (periodic sleeping sickness). In cases of narcolepsy there are frequent disturbances of nocturnal sleep and attacks of sudden muscular weakness caused by various emotions (catalepsy). Permanent hypersomnia, which is found in cases of neuroinfections, disruptions of cerebral blood circulation, and tumor processes, is manifested by constant sleepiness and falling asleep under natural, ordinary conditions. In contrast to patients with certain forms of paroxysmal hypersomnia, persons suffering from permanent hypersomnia are easily awakened. However, left to themselves, they quickly fall asleep again. The basis of all types of hypersomnia is disturbance of the functioning of the brain’s “wake-sleep” system. In addition to decreased wakefulness, disturbance of the regulation of the phases of “rapid desynchronized” and “slow synchronized” sleep plays an important role.

Treatment depends on the form of hypersomnia. In cases of narcolepsy, stimulators of the nervous system are used. In cases of periodic sleeping sickness and similar forms of hypersomnia, treatment includes general restorative therapy and checkup of respiratory and blood circulation functions. Treatment of permanent hypersomnia involves removal of the causes.

N. N. IAKHNO

Mentioned in ?
References in periodicals archive ?
The investigators showed further that the macrolide antibiotic clarithromycin, a negative allosteric modulator of GABA-A receptors, reduced sleepiness in patients with central hypersomnolence syndromes in a randomized, double-blind, crossover trial (Ann Neurol.
Bresch's critique, I think we should explore further the possibility that this patient may have delirium/sleep related ictal events on very high doses of clozapine; psychosis at lower doses; and a sleep disorder that has features of narcolepsy after a relative pharmacological wash out, remission of his psychotic symptoms, and improvements in drug induced sedation and hypersomnolence. Focusing on single hypotheses does not help explain the emergence of episodic vivid visual hallucinations, loss of muscle tone, or periods of intrusive sleep in the context of a clear sensorium and ongoing remission of other psychotic symptoms with lower doses of clozapine.
"I usually start my interview of patients with hypersomnolence with very careful, nonleading [questions about] cataplexy, because if the cataplexy is present, you have your diagnosis," Dr.
The patient should also be observed for confusion, especially upon awakening, and hypersomnolence during the day (inability to stay awake, falling asleep during a conversation or at other inappropriate times).
A diagnosis of SAS was established by the simultaneous presence of two criteria: subjective hypersomnolence, defined as >10 points on the Epworth sleepiness scale, and an increased apnea-hypopnea index, defined as more than five apnea or hypopnea episodes per hour of sleep during an overnight sleep study.
Her husband reported that she was a snorer, but she did not complain of significant daytime hypersomnolence. There was no history of epilepsy.
A large number of additional men and women are diagnosed as having idiopathic central nervous system hypersomnolence: likely due to yet other perturbations in brain chemistry, that eventuate in severe sleepiness without classic narcolepsy.
G, age 14, presents to the ED with hypersomnolence and altered mental status.
Modafinil decreases hypersomnolence in the English bulldog, a natural animal model of sleep-disordered breathing.
Complications of DM1 include muscle weakness, fatigue, hypersomnolence, cardiac conduction deficits, cognitive dysfunction, apathy, and gastrointestinal manifestations including dysphagia (Harper, 2001; Turner & Hilton-Jones, 2008).
(5) Mishra et al., during acute stage reported among 544 patients examined in OPD, 99% suffered with breathlessness, 95% with cough, 46% had choking and irritation, 25% had chest pain, 21% were listless, 16% suffered with hypersomnolence, 7% were brought in coma, 92% suffered with loss of appetite 52% had nausea and vomiting, 82 % had ronchi and crepts 80% had tachypnea, 54% had tachycardia and 2% had fever.
Hypersomnolence improved significantly after hyoid suspension from a median preoperative ESS of 10 (IQR 8-12) to a median postoperative ESS of 8 (IQR 6-9; gain -2; P < 0.05).