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Among these patients, two were complicationfree, whereas the rest had chronic complications, such as cholangitis, portal hypertension, variceal bleeding, hypersplenism, hepatopulmonary syndrome, and cholangioblastic hepatoblastoma.
Pancytopenia in chronic liver disease can be due to hypersplenism, megaloblastic anemia, and primary marrow suppression.
In patients with CLD, cytopenias were considered to be caused mostly due to hypersplenism .
Li et al., "Comparison of total splenic artery embolization and partial splenic embolization for hypersplenism," World Journal of Gastroenterology, vol.
Liver cirrhosis was clinically diagnosed using the morphologic appearance with portal hypertension, such as portosystemic shunt or hypersplenism on imaging or liver histology.
The 75 patients with LC had been diagnosed via liver ultrasound and CT and exhibited LC accompanied by portal hypertension and hypersplenism. The 90 patients with CHB satisfied diagnostic criteria based on guidelines for the prevention and treatment of chronic hepatitis B (2010 version) issued by the Chinese Society of Hepatology and the Chinese Society of Infectious Diseases of the Chinese Medical Association.
Considering the mechanisms of GS formation in cases of CLD [31-34], such as oversecretion of bilirubin due to increased hemolysis secondary to hypersplenism [35, 36] and impaired reduction of phospholipid and bile acid secretion compared to cholesterol secretion , it seems possible that GSD could develop in a young CLD patient and that the influence of liver disease on the prevalence of GSD is stronger than that of age.
He had also significant ALP and GGT elevations, portal hypertension, and hypersplenism findings at the time of diagnosis.
Splenic complications like hypersplenism, sequestration crisis, and infarction have been reported frequently in patients with SCD and its variants, including in sickle cell beta-plus thalassemia [7, 8].
Complications of CH include hypersplenism, malignancy and spontaneous rupture which is the most common complication and has been reported in 25% of cases.
The patients were divided into splenectomy group (n = 9), normal splenic function group (n = 24), and hypersplenism group (n = 16).
Hepatocellular functions are relatively well-preserved and complications are portal hypertension (PH), gastro-oesophageal varices and hypersplenism.1,5 Data regarding exact incidence and prevalence of CHF is not known, but estimated prevalence is 1 in 10,000 to 20,000.1,5 In 1978, Kerr reported 30 cases of CHF and described their long-term outcome.6 Poddar U.
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