hypersplenism


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hypersplenism

[‚hī·pər′sple‚niz·əm]
(medicine)
Condition caused by abnormal spleen activity.
References in periodicals archive ?
A total of 49 cases were classified into three groups according to splenic function: a splenectomy group, a normal splenic function group (control group), and a hypersplenism group.
Complications of CHF are variceal bleeding, hypersplenism, and cholangitis and, to a lesser extent, biliary stones and cholangiocarcinoma mainly reported in adult patients.
Splenectomy was performed due to hypersplenism in 38 (76%) patients, abdominal discomfort 9(18%), and splenic injury 3(6%) (Table-I).
15) Pancytopenia usually gets worse as the disease progresses because of a combination of bone marrow failure, hypersplenism, and/or hemophagocytosis associated with the disease.
Hypersplenism, septicemia, and gestational thrombocytopenia/DIC were the other common causes.
LCA patients can present with symptoms and signs of hypersplenism and bicytopenia (anemia and thrombocytopenia).
The moderately severe anaemia can be attributed to a combination of factors including hypersplenism, reticulo-endothelial iron blockade due to infection, and possible abdominal crisis.
Do not overlook the presence of abnormal populations or clones due to paroxysmal nocturnal haemoglobinuria or myelodysplasia, the impact of HIV or infiltrative lesions causing hypersplenism on the basis of congestive splenomegaly.
A milder late-onset form, presenting at any age from third decade onward, manifests in a manner similar to porphyria cutanea tarda (PCT) or variegate porphyria (VP), but may also cause thrombocytopenia secondary to hypersplenism.
Whilst the detection of this tumour in our patient was incidental, LCA may present with hypersplenism and could be associated with malignant tumours in 33% of cases (e.