When abundant, these can stand out sharply but they are often ill defined and rarely are they the robust luteinized cells of entities such as stromal hyperthecosis
or as seen in the stroma of diverse neoplasms.
Common androgen secreting ovarian tumors include Leydig cell neoplasm, stromal luteoma, Sertoli-Leydig cell tumor, and ovarian hyperthecosis .
Bilateral laparoscopic salpingo-oophorectomy revealed left stromal luteoma, bilateral stromal nodular hyperthecosis (see Figure 1), and right paratubular cysts.
Differential diagnosis includes granulosa cell tumor, thecomas, stromal hyperthecosis
, unclassified sex cord- stromal tumors, stromal luteomas and hyperreactio luteinalis (8).
False-positives identified for endometriosis by laparoscopy in this study population included fibrosis, inflammatory changes, normal peritoneum for peritoneal biopsy sample and for adnexal mass serous cysts, haemorrhagic cysts, corpus luteum cysts, normal ovarian stroma, ovarian hyperthecosis
Hughesdon, "Morphology and morphogenesis of the Stein-Leventhal ovary and of so-called 'hyperthecosis
'," Obstetrical and Gynecological Survey, vol.
The differential diagnosis for Kendra include: 1) ovarian hyperthecosis, 2) congenital adrenal hyperplasia, 3) Cushing syndrome, 4) androgen-producing neoplasms/adrenal carcinoma, and 5) polycystic ovarian syndrome.
Ovarian hyperthecosis. Ovarian hyperthecosis is the unusual proliferation of the ovaries that causes nests of luteinizing theca cells throughout the stroma (Chang, 2004).
Leydig cell tumor, non hilar type, is composed of steroid cells containing Reinke crystals and surrounded by ovarian stroma that often shows stromal hyperthecosis
, and except for their location, the clinical and pathological features of the non hilar type is similar to that of the hilar type.
(123) Other pseudotumors with an endocrine underpinning include prostatic hyperplasias, (124,125) focal nodular hyperplasia of the liver (126) (Figure 14, A through D), ovarian stromal hyperthecosis
, (127) the endometrial Arias-Stella reaction, (128) osteitis fibrosa cystica (brown tumor of hyperparathyroidism) (129,130) (Figure 15, A through D), and uterine cervical microglandular hyperplasia.
INTRODUCTION: Ovarian hyperthecosis refers to patches of leutinized theca--like cells scattered throughout the ovarian stroma.
Discrete nests of luteinized cells are seen in some places which is suggestive of ovarian hyperthecosis (Figure 3).