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McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.
There was asymmetrical septal hypertrophy in the mid segments measuring 22 mm, the anterior wall measured 16mm, whereas the inferior wall measured 14mm; producing mid cavity gradients of 50 mm of Hg, suggestive of hypertrophic cardiomyopathy. The echocardiogram was performed without doing Valsalva maneuver.
Ranolazine is an effective antianginal therapy for patients with hypertrophic cardiomyopathy (HCM).
Aeppli, "Clinical course of hypertrophic cardiomyopathy in a regional United States cohort," JAMA, vol.
Kamitani, "Usefulness of high-sensitivity cardiac troponin and brain natriuretic peptide as biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy," The American Journal of Cardiology, vol.
Isolated apical left ventricular hypertrophic cardiomyopathy had been detected in a 55-year-old South-Indian male who is a hypertensive and chronic smoker; 2D echocardiography confirmed the rare finding of isolated hypertrophy of the left ventricular apex.
* The report provides a snapshot of the global therapeutic landscape of Hypertrophic Cardiomyopathy
Recent advances in the molecular genetics of hypertrophic cardiomyopathy. Circulation 1995;92(5):1336-47.
Hypertrophic cardiomyopathy (HCM) is a structural and functional disease of the myocardium and is the most common cause of sudden cardiac death in young athletes.
BARCELONA -- Routine use of a new risk calculator tool to estimate the 5-year risk of sudden cardiac death is recommended in all patients with hypertrophic cardiomyopathy in updated guidelines launched at the annual congress of the European Society of Cardiology.
Objective: To study the therapeutic effects of low-dose amiodarone and Betaloc on hypertrophic cardiomyopathy complicated by malignant ventricular arrhythmias.
A Guide to Hypertrophic Cardiomyopathy: For Patients, Their Families, and Interested Physicians, 3rd Edition

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