hypnotic


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to hypnotic: Hypnotic drugs

hypnotic

a drug or agent that induces sleep

Hypnotic

 

any one of a group of drugs that induce sleep. In large doses hypnotics bring on a state of anesthesia. The effect they produce is the result of their inhibitory action on various parts of the central nervous system.

Hypnotics include substances differing in chemical structure, for example, such barbituric-acid derivatives as barbital, phenobarbital, barbital sodium, barbamil, barpental, and cy-clo’oarbital, such piperidine derivatives as Doriden, and such aliphatic compounds as chloral hydrate, carbromal, and bromi-sovalum. Drugs from other pharmacological groups also help normalize sleep; these drugs include sedatives, for example, bromides and valerian preparations, and tranquilizers, for example, diazepam (Seduxen), nitrazepam (Eunoktin), and chlor-diazepozide (Elenium). By diminishing emotional excitement and relieving tension and restlessness, sedatives and tranquilizers facilitate the onset of deep sleep.

Hypnotics are used with a variety of sleep disorders. Preparations with longer action, such as barbital and phenobarbital, are prescribed when an individual can fall asleep easily but soon awakens. When the difficulty consists in falling asleep but subsequent sleep is normal, barbamil, sodium pentobarbital, and Doriden are used. The sleep induced by most hypnotics differs considerably from natural sleep because the physiological succession of sleep periods is disturbed, with certain phases being suppressed. Thus, although barbiturates make it easy to fall asleep, they inhibit paradoxical sleep. If taken for a long time, they inhibit the paradoxical phase only at the start of treatment. Suspending the use of a hypnotic may markedly lengthen paradoxical sleep, intensify insomnia, and bring on nightmares.

The anesthetic action of hypnotics is slight, but they can intensify the effect of such nonnarcotic analgesics as amidopyrine and analgin, which are used with neuralgia. Hypnotics have a tranquilizing effect when used in doses that do not induce sleep. In doses exceeding therapeutic doses they may poison the body, causing the inhibition of breathing, a drop in body temperature and arterial pressure, a slowing of the pulse, and coma. Poisonings caused by hypnotics are treated by a series of measures aimed at maintaining breathing and the activity of the cardiovascular system and rapidly eliminating the drug from the body.

The daily use of long-acting hypnotics causes them to accumulate in the body, resulting in constant sleepiness, mental depression, and motor disorders. Prolonged ingestion decreases the body’s sensitivity to a hypnotic (habituation), which results in an even larger dose being needed to achieve the required effect. Drug dependence may also result.

REFERENCES

Zakusov, V. V. Farmakologiia, 2nd ed. Moscow, 1966. Pages 67–79.
Vein, A. M., and N. A. Vlasov. “Khimiia i farmakologiia sna” (bibliographic survey). Farmakologiia i toksikologiia, 1971, no. 3, pp. 369–80.
Mashkovskii, M. D. Lekarstvennye sredstva, 7th ed., part 1. Moscow, 1972.

V. V. CHURIUKANOV

hypnotic

[hip′näd·ik]
(pharmacology)
A drug which induces sleep. Also known as somnificant; soporific.
References in periodicals archive ?
It is therefore, difficult to ignore the role of hypnosis in high cessation rates of smoking being reported, and the clinical significance of the results that have been obtained.8 Evaluation of studies on the impact of hypnotic intervention on smoking cessation are not available in Pakistan.
That's when the subject enters an altered state of consciousness, a light, hypnotic state.
Usage data for two hypnotic drugs, zolpidem and triazolam, were extracted from health insurance records.
In relaxed state, there are theta brain waves that may be more prone for achieving hypnotic state.
Critique: An incredibly timely expose that will help to make sense out of today's political headlines and the Trump administrations alarming and otherwise bewildering support of Putin and seeming collaboration with Russia to the determent of America's European allies, "The Hypnotic Communist" is a compelling and informative read from beginning to end.
Persons Reporting Prescriptions for 10 Leading Psychiatric Drugs (a) Drug Name Mechanism Rank (Brand Name) of Action 1 Sertraline hydrochlolride SSRI (Zoloft) antidepressant 2 Citalopram hydrobromide SSRI (Celexa) antidepressant 3 Alprazolam (Xanax) Benzodiazepine 4 Zolpidem tartrate (Ambien) Hypnotic 5 Fluoxetine hydrochloride SSRI (Prozac) antidepressant 6 Trazodone hydrochloride SARI (Desyrel) antidepressant 7 Clonazepam (Klonopin) Benzodiazepine 8 Lorazepam (Ativan) Benzodiazepine 9 Escitalopram oxalate SSRI (Lexapro) antidepressant 10 Duloxetine hydrochloride SNRI (Cymbalta) antidepressant Reported Use, Prescriptions per Rank No.
These may be used as hypnotics. Mirtazapine is an anti depressant with sedative property, may be used as a hypnotic.
The fact of the matter is that the existence or nonexistence of a hypnotic state has been and still is the subject of 60 years of intensive research and debate in which there is little agreement (Accardi, Cleere, Lynn, & Kirsch, 2013; Kallio & Revonsuo, 2003; Kirsch, 2005; McConkey, 2008).
He said: "It's hypnotic, laugh a minute entertainment for all the family.
In America he's still a huge name but we've never quite known what to make of him in Britain and enjoyable though it is, Hypnotic Eye is unlikely to change things.
Miami, FL, September 25, 2013 --(PR.com)-- Ahmad A., Indiana resident and inventor, recently contracted invention assistance leader NewProductHelp.com to represent his Hypnotic Vehicle Accessories concept to industry over the next 2 years.