hypochlorhydria


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hypochlorhydria

[‚hī·pō‚klȯr′hī·drē·ə]
(medicine)
Reduction in the hydrochloric acid content of gastric juice.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
There is neither achlorhydria nor profound hypochlorhydria. This pattern is suggestive of a high level of duodenogastric reflux.
Likewise, hypochlorhydria and bacterial overgrowth in the mucosa can play an important role in the malabsorption process (8, 12).
Food-[B.sub.12] malabsorption is a syndrome characterized by the inability to release [B.sub.12] from food or intestinal transport proteins, particularly in the presence of hypochlorhydria, in which the absorption of "unbound" [B.sub.12] is normal.
Deficiencies of hydrochloric acid (hypochlorhydria) induce the production of gastrin-producing or G cells.
The study did not determine the mechanism behind the increased risk of hip fracture in PPI users, but the authors noted that these drugs may decrease calcium absorption via induction of hypochlorhydria, and may also reduce bone resorption by inhibiting the osteoclastic proton transport system.
IL-1[beta] induces chronic hypochlorhydria, which promotes the spread of HP-induced inflammation and leads to gastric atrophy, a precursor of gastric cancer (1).
"Although the clinical importance of these findings is fairly clear, the mechanism by which intestinal absorption of thyroxine is impaired in patients with hypochlorhydria is unknown.
In areas of developing countries where waterborne diseases are endemic, malnutrition associated with weaning, secondary hypochlorhydria, and increased exposure to contaminated water heighten incidence among the immunocompromised young, particularly those two to four years of age [14].
Such impairment includes loss of dentition, ageing changes in the oesophagus, impaired gastrointestinal motility, gastric atrophy and hypochlorhydria [34].
Comment: Gastric hydrochloric acid enhances the absorption of non-heme iron, and iron absorption is frequently impaired in people with hypochlorhydria. H.
The anemia may be attributable to decreased iron absorption secondary to hypochlorhydria or achlorhydria, blood loss, or vitamin [B.sub.12] deficiency in the setting of autoimmune metaplastic atrophic gastritis.
* Inability to absorb iron due to hypochlorhydria (maybe secondary to