The reduction in the production of one or more polypeptide chains generally results in the development and hypochromic microcytic anemia
. Since the reduction of the synthesis may be total or partial, thalassemias are classified according to the affected globin chain, alpha, beta, delta, delta-beta, and gamma-delta-beta.
Laboratory investigations were significant for hypochromic microcytic anemia
(Ht 29.3; normal range 42-54).
Peripheral blood examination showed hypochromic microcytic anemia
, anisocytosis, and target cells.
Erythrocytosis and a mild hypochromic microcytic anemia
characterize this heterozygous condition.
Methods: This descriptive study females of child bearing age visiting FMH OPD presenting with hypochromic microcytic anemia
were selected by non-probability purposive sampling and screened for beta thalassemia trait.