hypofibrinogenemia


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hypofibrinogenemia

[¦hī·po·fī¦brin·ə·jə′nē·mē·ə]
(medicine)
A decrease in plasma fibrogen level.
References in periodicals archive ?
At that time, the cause of anemia was contributed to her increased menstruation; however, the cause of her hypofibrinogenemia was unknown.
Hypertriglyceridemia in 53% and hypofibrinogenemia in 46%, elevated ferritin in 10 out of 13 cases (76%), Hemophagocytosis in bone marrow was found in 11 out of 13 (84%).
2 mm/h, (1-90 mm/h) Elevated transaminases, AST Mean 100 IU/L , (9-1 690 IU/L) ALT Mean 66 IU/L, (13-840 IU/L) Hypertriglyceridemia 9 (90 %), Mean 397[+ or -]332 mg/dL (78-1 260 mg/dL) Hypofibrinogenemia 4 (40%), Mean 321.
1) Complete diagnosis is made by identification of the abnormal genetic mutations or when five of the following eight diagnostic criteria are identified: fever, splenomegaly, cytopenias, hypertriglyceridemia and/or hypofibrinogenemia, hemphagocytosis, low or absent NK-cell activity, elevated ferritin, and elevated sCD25.
4) Laboratory features include markedly elevated ferritin, pancytopenia, prolonged PT and PTT, hypofibrinogenemia, elevated fibrin split products, and hypertriglyceridemia.
Three units of fresh frozen plasma were administrated within 3 days to the patient for the correction of severe hypofibrinogenemia despite a very high D-dimer level (5000 ng/mL), both of which reflected consumption coagulopathy, as stated by the authors.
Physical examinations did not detect splenomegaly, and laboratory findings did not show hypofibrinogenemia or ferritin level exceeding 500 ng/mL.
Acute Promyelocytic Leukemia (APML) is a distinct clinical entity frequently presenting with disseminated intravascular coagulopathy, hypofibrinogenemia, and hemorrhage.
rate / based on local currency (AUD) DRUGS APPROVED/LAUNCHED Drug Indication Panvax avian influenza (Australia) DRUGS PENDING APPROVAL Drug Indication Panvax avian influenza - pediatric (EU) Hemocomplettan congenital fibrinogen deficiency DRUGS IN PHASE IIB AND BEYOND Drug Indication csl718 primary immune deficiency IV immunoglobulin secondary recurrent miscarriage Beriplex blood coagulation disorders, acute major bleeding immunoglobulin G primary immune deficiency human fxlll factor XIII deficiency concentrate human fibrinogen afibrinogenemia, concentrate hypofibrinogenemia, fibrinogen deficiency zemaira emphysema caused by API deficiency TOP SELLING DRUGS Drug Indication $ (+/- %) Immunology $885 29% Plasma-derived $531 16% coagulants Recombinant FVIII $405 15% Biotherapies (incl.
Laboratory findings of high levels of ferritin, hypertriglyceridemia and hypofibrinogenemia can also be present, supporting the diagnosis.
Children with this severe, autosomal recessive immunodeficiency syndrome can develop hemophagocytic syndrome, with infectious episodes, and pancytopenia, hypertriglyceridemia, hypofibrinogenemia, and hypoproteinemia.