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see diabetesdiabetes
or diabetes mellitus
, chronic disorder of glucose (sugar) metabolism caused by inadequate production or use of insulin, a hormone produced in specialized cells (beta cells in the islets of Langerhans) in the pancreas that allows the body to use and store
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a decrease in the sugar content of the blood to below 80-70 mg percent.

Hypoglycemia is found in healthy persons during heightened muscular activity as a result of the considerable expenditure of glucose as an energy source when the body’s energy loss is not replenished with readily assimilable carbohydrates. Hypoglycemia sometimes arises after heavy intake of carbohydrates as a result of the reflex secretion by the pancreas of an excessive amount of insulin. The condition is observed in certain diseases of the insular apparatus of the pancreas, the hypothalamic region of the brain, the other endocrine glands, or the liver (disruption of the liver’s function as the principal glycogen depot), as well as in insulin overdose (hypoglycemic shock). In hypoglycemic shock, after a short period of central nervous system excitation, a condition develops that is accompanied by weakness, drowsiness, hunger, and psychic disturbances. Trembling, loss of consciousness, and convulsions may set in when sugar content is lowered to 40 percent or less. The condition is eliminated by administering glucose. Hypoglycemic or insulin shock may be induced artificially for the treatment of certain diseases.


Genes, S. G. Gipoglikemiia: Gipoglikemiche skii simptomokompleks. Moscow, 1970. (Bibliography, pp. 224-35.)
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Condition caused by low levels of sugar in the blood.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
In the study IN CONTROL real time CGM increased time spent in normoglycaemia and reduced severe hypoglycaemia in adult patients with type 1 diabetes and impaired awareness of hypoglycaemia, compared with self monitoring blood glucose (30).
One study recommended that infants must be screened at 4-6 hours of life, with an emphasis that no studies demonstrated harm from fewer hours of hypoglycaemia, [17] and another study demonstrated that IDM have asymptomatic hypoglycaemia in the first hour, thus supporting earlier screening in these infants and to stop after 12 hours, if glucose levels remain above 2.6 mmol/L.
To study the knowledge on early management of hypoglycaemia among patients with diabetes and their caregivers.
Infants and toddlers are likely to have erratic and unpredictable eating and activity patterns, may be unable to communicate their symptoms or understand the need for intervention and may refuse blood glucose monitoring and insulin injections.4 Furthermore, there is increased risk of unpredictable hypoglycaemia and inter-current illnesses, such as respiratory or gastrointestinal infections, requiring more frequent sick day management.3,4 In Table 1, we enlist the unique challenges with regards to subcutaneous insulin administration in infants and toddlers and offer pragmatic solutions.
It is in development in the ready-to-use HypoPal rescue pen for easy, fast and effective treatment of severe hypoglycaemia.
Also, severe hypoglycaemia was evaluated as a secondary endpoint and 27% fewer patients in the Tresiba treated group experienced an episode of severe hypoglycaemia, resulting in a 40% overall rate reduction of total episodes of adjudicated severe hypoglycaemia.
Kahn, "The riddle of tumour hypoglycaemia revisited," Clinics in Endocrinology and Metabolism, vol.
Tresiba is a once-daily basal insulin for people with diabetes that achieves reductions in blood glucose levels with a lower risk of nocturnal hypoglycaemia equivalent to insulin glargine1, 2.
Diabetes UK has welcomed changes to the rules and said that European laws introduced meant drivers who treat their diabetes with insulin who have had one or more episodes of severe hypoglycaemia, known as "hypos", could face losing their licences.
It said that European laws introduced in 2011 meant that drivers who treat their diabetes with insulin who have had one or more episodes of severe hypoglycaemia, known as "hypos", could face losing their licences.
[1] Some of these new therapeutic agents, the incretins, have been shown to lower traditional cardiovascular risk factors and also mitigate newly identified risk factors such as hypoglycaemia and weight gain, both of which often develop as adverse effects when tight glucose control is achieved.
ISLAMABAD -- Even hypoglycaemia, which occurs when a patient's blood glucose becomes dangerously low, can trigger potentially fatal cardiovascular events.