The study focused on the safety and feasibility of stem cell treatments designed to strengthen the heart muscle of children with hypoplastic
left heart syndrome, a severe congenital heart disease.
Harold Burkhart, who leads the pediatric cardiothoracic surgery team at OU Medicine, said being a member of the Hypoplastic
Left Heart Syndrome Consortium establishes Oklahoma as a regional center for families to receive care closer to home.
The other important feature of this syndrome is hypoplastic
In utero valvuloplasty for pulmonary atresia with hypoplastic
right ventricle: Techniques and outcomes.
Two or more asymmetric parameters were found in 67% of women with hypoplastic
breasts, 65% of women with macromastia, and 68% of women with ptotic breasts.
Interestingly, all cases of hypoplastic
marrow 12 cases (5.4%) had history of herbal medicine intake.
The study--"Allogeneic hMSC Injection in Patients With Hypoplastic
Left Heart Syndrome (ELPIS)"--is an open-label clinical trial enrolling 30 infants with HLHS overseen by Longeveron, a Miami-based regenerative medicine company, the University of Maryland, and Johns Hopkins University.
The clinical presentation of a hypoplastic
thumb varies from moderate hypoplasia to the loss of the thumb.
However, it must be kept in mind that hypoplastic
calvaria strongly indicates phases of arterial hypotonia and subsequent hypoxia during fetal development.
In this group of CLA, formation of the petrous bone is normal, but the otic capsule is hypoplastic
right A1 variant was associated with the hypoplastic
left A1 (p < 0.0001) and a hypoplastic
right A2 (p = 0.002), with statistical significance.
Under the terms of the grant agreement, the company will partner with the University of Maryland and Johns Hopkins University to conduct a clinical trial for Hypoplastic
Left Heart Syndrome (HLHS), a rare and often fatal condition in infants caused by an underdeveloped heart.