hypoprothrombinemia


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hypoprothrombinemia

[¦hī·pō‚prō¦thräm·bə′nē·mē·ə]
(medicine)
Deficiency of prothrombin in the blood.
References in periodicals archive ?
A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome.
Steroids or intravenous immunoglobulin has proved beneficial in LA patients with hypoprothrombinemia syndrome (LA antibodies directed against prothrombin) who either have bleeding or need surgery.
Hypoprothrombinemia and hemorrhage associated with cholestyramine therapy.
His illness was clinically marked by progressive renal failure, bilateral pulmonary infiltrates, acidosis, abnormal liver function test results, thrombocytopenia, and hypoprothrombinemia.
Inhibitors usually associated with hemorrhage Antifactor VIII, II, IX, X, XI Anti-Willebrand factor Antifibrinogen/fibrin Heparin-like anticoagulants Inhibitor variably associated with hemorrhage (from trivial to life-threatening) Antifactor V Inhibitors usually not associated with hemorrhage LA (with the possible exception of an association with hypoprothrombinemia) Antifactor XII Table 2.
However, existing case reports of increased hypoprothrombinemia with bleeding due to this interaction warrant careful monitoring of PT, preferably with the international normalized ratio (INR), when using these agents concurrently.
Fat-Soluble Vitamins Vitamin A Missing or underdeveloped eyes; hydrocephalus; cardiovascular anomalies; urogenital anomalies; diaphragmatic hernia Vitamin D Skeletal abnormalities Vitamin D Skeletal abnormalities Vitamin E Anencephaly; umbilical hernia; club feet; cleft lip Vitamin K Brain hemorrhages; hypoprothrombinemia