(2) showed that patients with hypospermatogenesis
were more likely to benefit from varicocelectomy.
In the AZFc region, partial deletion of DAZ gene caused hypospermatogenesis
Since there was no information regarding TESE(-) subdivision, it was suggested that the closest classified group to TESE(+) and fertile group was hypospermatogenesis
. The other two groups were maturation arrest or germinal aplasia (Sertoli-cell-only syndrome) (22).
Varicocele: Relation between anoxia and hypospermatogenesis
. Int J Fertil 1977;22:174-8.
The severities of spermatogenic arrest and hypospermatogenesis
have been reported to be correlated with VC duration .
, who found sperm in 100% of 76 repeated sperm retrieval procedures (TESA, PESA, and TESE) in men with obstructive azoospermia, and with Hussein , who found a decreased chance of finding sperm by repeat sperm retrieval in men with hypospermatogenesis
and maturation arrest.
Cytological Findings Indices Interpretation Most of native cell Sertoli index 50% or Normal seen below Spermatic index 50% or below Most of native cells Sertoli index above Hypospermatogenesis
seen 50% Spermatic index 50% or below Germ cells identified Sertoli index 50% or Maturation arrest only to a particular below Spermatic index level of maturation zero Germ cells identified Sertoli index above Maturation arrest only to a particular 50% Spermatic index +Hypospermatogeneis level of maturation zero Spermatozoa out Sertoli index 50% or Duct obstruction number other native below Spermatic index cells above 50% Sertoli cells only Sertoli index 100% Total atrophy/ seen Spermatic index zero Sertoli cell only syndrome * Spermatic index (Number of spermatozoa per 100 spermatogenic cells.
Studies have observed that testicular biopsies from infertile Nigerian men showed a variety of pathological conditions; the most prevalent was hypospermatogenesis
. Patients without testicular biopsies had clinically detectable testicular or epididymal abnormalities.
A: In one of our studies, we determined the reproductive hormones and morphological changes induced by mobile phone radiation and found that long-term exposure to mobile phone radiation leads to reduction in serum testosterone levels and cause hypospermatogenesis
and maturation arrest in the spermatozoa in the testis of albino rats.
, and hypertension).
It is then possible to speculate that this reduced expression could lead to lactate deprivation in germ cells with subsequent hypospermatogenesis
BACKGROUND: In utero exposure to endocrine-disrupting chemicals may contribute to testicular dysgenesis syndrome (TDS), a proposed constellation of increasingly common male reproductive tract abnormalities (including hypospadias, cryptorchidism, hypospermatogenesis
, and testicular cancer).