(redirected from hypoxic-ischemic encephalopathy)
Also found in: Dictionary, Thesaurus, Medical.


Any disease of the brain.



a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
Hypoxic-ischemic encephalopathy (HIE) is brain injury that occurs because of a lack of adequate blood flow during the prenatal, perinatal, or postnatal period (Volpe, 2001).
Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy.
Louis Children's Hospital, conducted a randomized trial among 69 neonates of at least 36 weeks' gestational age who had moderate to severe hypoxic-ischemic encephalopathy (HIE).
A snapshot of the global therapeutic scenario for Hypoxic-Ischemic Encephalopathy.
Electrographic seizures during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy.
Comparison of S100 protein and MDA concentrations in blood of newborns and infants with hypoxic-ischemic encephalopathy demonstrated difference in the parameters by a type of cerebral ischemic syndrome.
An MRI scan subsequently showed widespread brain damage - he was diagnosed with a condition called hypoxic-ischemic encephalopathy, usually caused by being deprived of oxygen at birth.
In our study we used Hypoxic-ischemic encephalopathy score postulated by Thompson et al.
The children in the study had suffered moderate or severe hypoxic-ischemic encephalopathy (HIE) at birth, but it was only children with moderate HIE that were helped by this hormone treatment.
The clinical courses and cerebral findings of these survivors are similar to those seen with perinatal hypoxic-ischemic encephalopathy (so-called cerebral pal sy).
Coverage begins with human brain development and proceeds through neurological evaluation, hypoxic-ischemic encephalopathy, intracranial hemorrhage, metabolic encephalopathies, disorders of the motor system, intracranial infections, perinatal trauma, intracranial mass lesions, and drugs and the developing nervous system.
A patient registry is part of the Food and Drug Administration approval of the "Cool-Cap" device for treating full-term newborns with moderate to severe hypoxic-ischemic encephalopathy.