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McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The additive prognostic value ofrestrictive pattern and dipyridamole-induced contractile reserve in idiopathic dilated cardiomyopathy. Eur J Heart Fail 2005; 7(5):844-51.
Idiopathic dilated cardiomyopathy. N Engl J Med 1994; 331: 1564-1575, doi: 10.1056/NEJM 199412083312307.
A novel mitochondrial DNA tRNAIle (m.4322dupC) mutation associated with idiopathic dilated cardiomyopathy. Diagn Mol Pathol 2007;16:238-42.
We report a case of urinary tract infection due to Trichosporon asahii in an 80-year-old male patient with idiopathic dilated cardiomyopathy. Yeast-like organisms were isolated from urine samples on three consecutive days as pure cultures.
Objective: To prospectively assess the safety and efficacy of ivabradine in patients with idiopathic dilated cardiomyopathy. Methods: We included 35 patients with idiopathic dilated cardiomyopathy with an ejection fraction (EF) <40% and heart rate >70 beats/min despite optimal medical therapy, according to the international guidelines in this prospective, non-randomized, single-arm, open-label safety study.
Epidemiology of idiopathic dilated cardiomyopathy and hypertrophic cardiomyopathy: a population-based study in Olmsted Country, Minnesota, 1975-1984.
Mechanisms of increased vascular super-oxide production in an experimental model of idiopathic dilated cardiomyopathy. Arterioscler Thromb Vasc Biol 2005;25:2554-2559.
The mean baseline ejection fraction in 50 patients diagnosed with idiopathic dilated cardiomyopathy was 44%.
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
The clinical characteristics and natural history of adults with idiopathic dilated cardiomyopathy are well described.
(14.) Zachara E, Caforio AL, Carboni GP, et al Familial aggregation of idiopathic dilated cardiomyopathy: clinical features and pedigree analysis in 14 families.

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