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Related to idiosyncrasy: drug idiosyncrasy


Med an abnormal reaction of an individual to specific foods, drugs, or other agents



a painful reaction that appears in certain persons to irritants that do not produce similar phenomena in the majority of others. The basis of idiosyncrasy is either a congenital increased sensitivity of the autonomic nervous system to particular irritants or a reaction that arises in the body as a result of the repeated weak action of certain substances that are incapable of stimulating antibody production in the body.

Idiosyncrasy differs from allergy in that it may develop even after the first contact with an intolerable irritant—for instance, simple chemical compounds that do not have the properties of allergens; such food products as fish, roe, crab, milk, eggs, and strawberries; such medications as amidopyrine, antibiotics, and sulfanilamide preparations; the pollens of certain flowers and plants; the odor of various animals; insect poisons; and such physical factors as sunstroke, chill, or trauma.

Soon after contact with the irritant, headache appears in the individual, and his temperature rises, sometimes accompanied by mental agitation, disruption of the function of the organs of digestion (nausea, vomiting, diarrhea) and respiration (dyspnea, coryza), edema of the skin and mucosa, and urticaria. These phenomena, which are caused by disruptions of blood circulation, increased permeability of the vessels, and spasms of the smooth musculature, usually pass quickly, but sometimes may continue for several days. The reaction does not produce insen-sitivity to the repeated action of the agent. Treatment requires avoidance of further contact with the intolerable irritant and lowering the body’s heightened reactivity.



A peculiarity of constitution that makes an individual react differently from most persons to drugs, diet, treatment, or other situations.
Any special or peculiar characteristic or temperament by which a person differs from other persons.
References in periodicals archive ?
As artists and adopted Liverpudlians aware of the historical links between the two cities, we felt the need to tell a story about some aspects of Shanghai's idiosyncrasy," they continue.
The first three chapters introduce inclusive leadership and the idiosyncrasy credit model of leadership and place it in the context of classic and current leadership research.
Both pieces immerse Curran in singular style, but they lack the idiosyncrasy of his 1998 Each of Both, a piece with searching emotional themes that are not as well developed as those of Five, but which do point him in the right direction.
He adds, "With modern autoverification, rules are written into the software so the technologist does not have to memorize every idiosyncrasy.
Which, no doubt, is a forgone conclusion for fans of detail-fixated English idiosyncrasy.
Schmelling allows for both readings, using his privileged position as semiofficial interloper (he also worked on some of the cleanup crews) to preserve the intimate details of another's private idiosyncrasy.
The work presented inside each introverted gallery is informed by mobility and cr oss-fertilization, by the interpenetration of infrastructure with the flow and idiosyncrasy of real life.
That's the Latin logistics idiosyncrasy that manufacturers, shippers and others in the industry hope to change.
Like It Is is no Beautiful Thing: Writer Robert Gray lacks Jonathan Harvey's wit and instinct for idiosyncrasy.
Another idiosyncrasy of the traditional airline fare structure is the existence of as many as 15 or more different fares between the same two cities.