- antiidiotypic relationship of neurotropic autoantibodies in patients with mild closed head injury.
However, if the genotypes change drastically, as by introduction of a new idiotype
, a new assessment of mega-environments is needed.
Neutralizing ADAs block the idiotype
of the drug molecule directly or by steric hindrance, with sufficient strength to interfere with, or eliminate, the activity of the drug.
Instead, they reported that the foreign gene was not turned on in most of the cells, but rather it had somehow influenced the mouse's own genes to mimic the foreign gene's idiotype
can provoke anti-idiotypes
, which in turn can provoke anti-idiotypes
that attach to the initial provoker as well as to the anti-idiotype
Bayer's personalised idiotype
vaccine for the treatment of Non-Hodgkin's-Lymphoma (NHL) is currently in Phase I clinical trials, and the cooperation is related to the development of a personalised Non-Hodgkin's-Lymphoma vaccine.
Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype
and carrier antigens.
We hypothesize that the interfering antibody in the Olympus ferritin assay is a natural antiidiotypic antibody that binds to a unique idiotype
on the rabbit antihuman ferritin antibody linked to latex (5).