immunoassay


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Immunoassay

An assay that quantifies antigen or antibody by immunochemical means. The antigen can be a relatively simple substance such as a drug, or a complex one such as a protein or a virus. See Antibody, Antigen

The reactants are first mixed so that a varying quantity of one (A) is added to a constant amount of the other (B). The formation of an immune (antigen-antibody) complex is measured as a function of the varied reactant (A). The result is represented by a “standard curve” for reactant A. An unknown sample is tested by adding it to reactant B. The extent of the measured change is referred to the standard curve, and thereby is obtained the amount of reactant A which produces a comparable change. The amount is represented as the content of reactant A in the unknown sample. See Immunofluorescence, Immunology, Radioimmunoassay

immunoassay

[‚im·yə·nō′a‚sāy]
(immunology)
A laboratory detection method that uses antibodies to react with specific substances.
References in periodicals archive ?
The report on global Immunoassays in R&Dmarket has given an in-depth study in some new and prominent industry trends, competitive analysis, and detailed regional analysis for the review period of 2019-2024.
Used in conjunction with the company's currently available FastPack Total Testosterone Assay, the SHBG Immunoassay will provide clinicians with a more complete picture of their patients' androgen status, particularly in the area of men's health and testosterone deficiency, stated CEO Michael S.
An evaluation of the diagnostic accuracy of liquid chromatography-tandem mass spectrometry versus immunoassay drug testing in pain patients.
Biotin interference has been a risk since streptavidin-biotin methods first began to be used in immunoassays decades ago.
[2] Nonstandard abbreviations: EMIT, enzyme multiplied immunoassay technique; CEDIA, cloned enzyme donor immunoassay; LOCI, luminescent oxygen channeling immunoassay; miRNA, microRNA; qRT-PCR, quantitative RT-PCR; AD, Alzheimer disease.
Mass spectrometry measurements of prostate specific antigen (PSA) peptides derived from immune-extracted PSA provides a potential strategy for harmonizing immunoassay differences.
"This advance opens many new and exciting opportunities for immunoassays and other detectors, as well as in disease early detection and treatment," said Stephen Chou, the lead researcher.
they could only be seen with a powerful electron microscope, the scientists were able to drastically increase the fluorescence signal compared to conventional immunoassays, leading to a 3-million-fold improvement in the limit of detection.
DBI is driving the widespread adoption of protein biomarker analysis with the first automated, multiplex immunoassay system that can be used in real-time by virtually anyone, anywhere in drug development, clinical trials and diagnostics.
Jerald Nelson and associates at Loma Linda (Calif.) University reported that a free [T.sub.4] immunoassay measured total [T.sub.4], not free [T.sub.4] (Clin.
The available immunoassays "all have problems," says Dr.
The scientists used a lateral flow-based immunoassay and viable plate counting to make the comparison.