immunoassay

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Immunoassay

An assay that quantifies antigen or antibody by immunochemical means. The antigen can be a relatively simple substance such as a drug, or a complex one such as a protein or a virus. See Antibody, Antigen

The reactants are first mixed so that a varying quantity of one (A) is added to a constant amount of the other (B). The formation of an immune (antigen-antibody) complex is measured as a function of the varied reactant (A). The result is represented by a “standard curve” for reactant A. An unknown sample is tested by adding it to reactant B. The extent of the measured change is referred to the standard curve, and thereby is obtained the amount of reactant A which produces a comparable change. The amount is represented as the content of reactant A in the unknown sample. See Immunofluorescence, Immunology, Radioimmunoassay

immunoassay

[‚im·yə·nō′a‚sāy]
(immunology)
A laboratory detection method that uses antibodies to react with specific substances.
References in periodicals archive ?
For the immunochemical assays we used a previously described in-house prepared polyclonal rabbitantihepcidin-25 antibody (17).
Contract notice: Delivery of reagents, calibrators, controls and consumables along with the lease centrifuge, laboratory refrigerators, sorter and two laboratory samples and analytical platforms analyzer immunochemical assays.
While CombiMatrix has been concentrating on DNA array biochips as its initial commercial application, the SBIR grant program has allowed us to demonstrate that ArrayChip technology can be just as easily applied to immunochemical assays for chemical and biological warfare agents.
Problem # 3 - Delivery of reagents with the lease of immunochemical assays analyzerProblem # 4 - Supply of reagents with the lease of the analyzer to carry out tests of general intelligence.
More recently, immunochemical assays for FLCs have been developed, and 1 study showed that the ratio of urine free [kappa] to [lambda] in combination with urine protein electrophoresis was clinically useful (11).
AMEX: LFP), announced today the filing of a patent containing 33 broad claims that can enhance the sensitivity of immunochemical assays by preventing or reducing the adsorption of molecules to solid assay surfaces.
Contract award: rent camera, delivery reagents, calibrators and control materials and consumables immunochemical assays.
Achieving reliable results in these immunochemical assays requires adherence to a strict preanalytical protocol that includes careful venipuncture, centrifugation of the sample within 1-2 h after venipuncture, addition of EDTA for stabilization of nucleosomes, and storage at -70[degrees]C if measurement is to be delayed.
This Phase I grant, entitled "Antibodies to New Amplified Breast Cancer Gene Products," supports research to create antibodies to novel amplified breast cancer gene products that will be used for immunochemical assays.
Dye-binding assays can measure serum albumin but are too insensitive for MAU testing, making immunochemical assays the most widely used MAU methods (8).
Immunochemical assays and Western blot data showed distinctive protein bands,
Contract notice: Rent 2 instruments immunochemical assays with the delivery of reagents.