immunoglobulin domain


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immunoglobulin domain

[‚im·yə·nō‚gläb·yə·lən də′mān]
(immunology)
The basic structural unit of immunoglobulins.
References in periodicals archive ?
NASDAQ: ALPN) has released results of a preclinical study of novel immuno-oncology molecules derived from the company's variant immunoglobulin domain platform, the company said.
Briefly, The templates used for modeling of immunoglobulin domain (pdb ID:2C5D), fibronectin type 3 domain (pdb ID:4PBX) and protein tyrosine kinase domain (pdb ID:3QUP) was found from RCSB protein data bank [21] based on high sequences homology and designed individually.
based therapies using its variant immunoglobulin domain (vIgD) platform technology.
Molecular structure of these proteins is similar to that of immunoglobulins having a domain known as an immunoglobulin domain or fold.
The extracellular part of Ror proteins contains an immunoglobulin domain, a cysteine rich domain, also called a frizzled domain and a kringle domain (3-7).
Jovine's team solved the structure of a mouse ZP-N region and found that the type of fold in the ZP-N is a twist on a protein shape called the immunoglobulin domain, which is well-known for its presence in antibodies.
The researchers' findings appeared in the June 20, 2006, edition of the journal PLoS Biology under the title "AgDscam, a Hyper Variable Immunoglobulin Domain Containing Receptor of the Anopheles gambiae Innate Immune System.
NASDAQ: ALPN) has released results from preclinical studies evaluating ALPN-101 program dual ICOS/CD28 antagonists generated by the company's variant immunoglobulin domain platform, the company said.
More detailed information of their function and associated pathways will serve to clarify their relationship to vertebrate immunoglobulin domain receptors.
Alpine Immune Sciences is focused on developing novel protein-based immunotherapies using its proprietary variant immunoglobulin domain platform technology.
Paramphinome jeffreysii 1 and Hemithris psittacea 2) included immunoglobulin domains (Fig.
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