immunologic tolerance


Also found in: Dictionary, Thesaurus, Medical, Legal.
Related to immunologic tolerance: oral tolerance

immunologic tolerance

[¦im·yə·nə¦läj·ik ′täl·ə·rəns]
(immunology)
A condition in which an animal will accept a homograft without rejection.
A state of specific unresponsiveness to an antigen or antigens in adult life as a consequence of exposure to the antigen in utero or in the neonatal period.
References in periodicals archive ?
mTOR inhibitors induce anergy in naive T cells, promote the expansion of regulatory T cells, and inhibit the maturation of dendritic cells, thus promoting immunologic tolerance.
3) "If we lose our connection to environmental microbiota, there may be adverse consequences to our immunologic tolerance," explains Hanski.
After 12 to 54 months of therapy, 17% of REPLAGAL treated patients were antibody positive whereas 7% showed evidence for the development of immunologic tolerance, based on the disappearance of IgG antibodies over time.