immunological memory


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Related to immunological memory: immunological tolerance

immunological memory

[‚im·yə·nə¦läj·ə·kəl ′mem·rē]
(immunology)
The capacity of the immune system to respond more rapidly and vigorously to the second contact with a specific antigen than to the primary contact.
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This is sometimes referred to as immunological memory or cell memory because the immune system will "remember" the antigens associated with that particular pathogen to which it was previously exposed and thus can initiate the immune response and eliminate the threat much more quickly the next time it is exposed to that pathogen.
To further investigate the importance of Oct1 and OCA-B in immunological memory, the researchers examined mice lacking either one of the two genes.
After the infection has resolved, some of these plasma cells may persist for 50 years or longer as memory B cells, which contribute to immunological memory and can respond quickly by producing antibodies if they encounter the same pathogen again.
Influenza virus-specific immunological memory is enhanced by repeated social defeat.
Pearce added: "We serendipitously discovered that the metabolizing, or burning, of fatty acids by T-cells following the peak of infection is critical to establishing immunological memory. We used metformin, which is known to operate on fatty-acid metabolism, to enhance this process, and have shown experimentally in mice that metformin increases T-cell memory as well as the ensuing protective immunity of an experimental anti-cancer vaccine."
Extensively updated, the textbook includes new chapters on innate and adaptive immunity, enhanced treatment of aspects of innate immunity such as the complement system and defensins, immunotherapies, and the nature of immune response in mucosal tissues and immunological memory. It is well-illustrated and includes essay, multiple choice, and case study questions at the conclusion of each chapter.
Cytokine detection assays are based on the observation that lymphocytes with immunological memory produce interferon-gamma (INF-[gamma]) when re-exposed to a specific antigenic challenge.
As a conjugate vaccine, Prevenar helps provide protection that was previously unavailable to infants and young children by stimulating the immune system and helping to create immunological memory.