immunosuppressive


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immunosuppressive

[¦im·yə·nō·sə′pres·iv]
(pharmacology)
Any drug or agent used to suppress antibody production.
References in periodicals archive ?
A majority of patients do not benefit from checkpoint inhibitors as many cancers are adept at evading or dampening an immune response through multiple mechanisms, including activation of immunosuppressive metabolic pathways.
Cytomegalovirus (CMV) is a well-known cause of life-threatening opportunistic infection in immunocompromised patients, such as those with acquired immunodeficiency syndrome (AIDS), receiving immunosuppressive therapy and those having undergone organ transplantation.
sup][1] In general, immunosuppressive therapies are effective in inducing remission in AIH patients.
As currently crafted, the Proposed Rule would enable Part D sponsors to impose formulary restrictions on immunosuppressive drugs, resulting in substantial risk of organ rejection, serious side effects, and adverse drug reactions for Medicare Part D beneficiaries who are transplant recipients.
However, cell graft survival seems to greatly depend on an accompanying immunosuppression regimen, yet there are differential responses to identical immunosuppressive therapies.
Their first set of guidelines addresses vaccination in children on immunosuppressive medications:
In a study on these rare individuals, researchers have identified a pattern of genes turned on in their white blood cells, which may one day be used to help identify other transplant recipients who could reduce or completely taper their immunosuppressive therapy without ill effect.
Following transplantation, immunosuppressive medicines are required to protect the transplanted organ from being rejected by the recipient's immune system.
5 mg of methotrexate per week and 5 mg of prednisone per day--the stakes have become higher as increasingly complex immunosuppressive therapeutic regimens are used, said Dr.
Patients receiving immunosuppressive agents are also predisposed to H.
In some patients, the transplanted mesenchymal cells appeared to have immunosuppressive and possibly anti-inflammatory effects that shut down GVHD.
CellCept is Roche's leading immunosuppressant or "anti-rejection" drug used in combination with other immunosuppressive drugs (cyclosporine and corticosteroids) for the prevention of rejection in patients receiving heart, kidney and liver transplants.