immunotoxicity

immunotoxicity

[‚im·yə·nō·täk′sis·əd·ē]
(immunology)
Adverse effects on the normal functioning of the immune system, caused by exposure to a toxic chemical. The result can be higher rates of infectious diseases or cancer, more severe cases of such autoimmune disease, or allergic reactions.
References in periodicals archive ?
A summary measure for coplanar (dioxin-like) polychlorinated biphenyls (cPCBs), which included congeners with suspected immunotoxicity (Wolff et al.
Microcystins may also impact the immune system of aquatic organisms but mechanisms of MC's immunotoxicity are currently poorly understood (Qiao et al.
Doctoral level subject matter experts (SMEs) in endocrine disruption, ecotoxicity, developmental toxicity, genotoxicity, immunotoxicity, and quantitative structure activity relationships make up the 2 branches of the Portfolio (Toxicity Evaluation Program; Health Effects Research Program).
Immunotoxicity, clinical/ preclinical requirements and regulatory issues are realistic hurdles which may limit the market penetration of peptide vaccines at global level.
Award: Potential for environmental and therapeutic agents to induce immunotoxicity
lead is now known to produce a spectrum of injury that causes loss of cognition, shortening of attention span, alteration of behaviour, dyslexia, attention deficit disorder, hypertension, renal impairment, immunotoxicity and toxicity to the reproductive organs.
Protective effects of different antioxidants against endosulfan-induced oxidative stress and immunotoxicity in albino rats.
Specialists in nanomedicine, nanotechnology, and translational bio-nanotechnology in academia, government, industry, consulting organizations, and regulatory agencies in the US, Europe, Australia, and India address topics such as nanoparticle interaction with erythrocytes, endothelial cells, various types of antigen-presenting cells, complement activation, platelets and the plasma coagulation system, bone marrow cells, nanoparticle use for drug delivery and vaccine adjuvants, sterility and sterilization, the presence of surface contaminants, regulatory considerations for the screening of nanoparticle toxicity to the immune system, the use of animal models to study nanoparticle immunotoxicity, and material characterization.
Kenny Bock, described in his book Healing the New Childhood Epidemics, include mitochondrial toxicity, metabolic toxicity, neurodevelopmental toxicity, and immunotoxicity, to name a few.
Immunotoxicity testing showed that there was no treatment-induced alloantibody formation or induction of autoimmunity.
presents 26 chapters detailing methods and protocols for immunotoxicity testing.