This active ingredient acts by interfering with the impulse transmission
in the nervous system and results in the eventual death of the pests.
2-4] Impulse transmission
in the visual pathway might be affected by ID.
Among the topics are polyacrylamide hydrogels obtained by frontal polymerization and their properties, fulvic and humin acids in surface waters of Georgia, modeling the physical mechanism of activation (opening) of ion channels in nerve impulse transmission
, and the thermal curing of composite-based epoxy.
Importantly, quantitative tests of specific sensory function, as well as electrophysiological measures of impulse transmission
across the site of injury, show an association with the clinical examination, providing further objective confirmation of the sensory gains.
The grant will support neuroscience in 13 core areas, including stem cells, proteomics, crystallography and nuclear magnetic imaging work, structural biology, functional genomics, genetic analysis, neurobehavior in mice, diseases of nerve cells, electrophysiology studies of nerve impulse transmission
, drug screening, and biostatistics and computational modeling.
In a key event during nerve impulse transmission
glutamate is released from vesicles in the presynaptic neuron, and travels across the synapse to glutamate receptors on the postsynaptic neuron (AMPA, NMDA and KA), resulting in depolarization of the postsynaptic neuron and generation of a postsynaptic action potential.
It's also needed for healthy nerves because it regulates the level of calcium in the blood which is vital for nerve impulse transmission
The changes in sensory function were confirmed objectively by measures of electrical impulse transmission
across the site of injury, each of which correlated with the clinical examination.
Thus, together, molecular batteries and nerve insulation have a powerful effect on the speed and efficiency of impulse transmission
within the nervous system.
Importantly, tests of perception of different sensory stimuli as well as measures of electrical impulse transmission
across the site of injury correlate with the clinical examination, providing independent and objective confirmation of the changes in sensory function.