melanoma

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melanoma:

see skin cancerskin cancer,
malignant tumor of the skin. The most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Rarer forms include mycosis fungoides (a type of lymphoma) and Kaposi's sarcoma.
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Melanoma

 

melanoblastoma; a malignant tumor that consists of melanin-producing cells.

Factors conducive to the development of melanomas include injury and hormonal stimulation, especially during puberty. Melanomas generally occur on the skin; less often, they appear on the retina, pia mater, nasopharynx, larynx, esophagus, and mucosa of the intestine and other organs. Melanomas usually develop at the site of pigmented or depigmented birthmarks, but they may also appear elsewhere. The process starts with a barely perceptible, painless tumor on the skin, sometimes resembling a wart, which gradually becomes dark brown or black. Occasionally, it ulcerates and bleeds. In case of injury, the tumor may enlarge quickly and become tuberous, dense at the base, and stiffer. The regional lymph nodes enlarge. The initial signs that a melanoma is developing at the site of a birthmark are the birthmark’s enlargement, an intensification or reduction in its pigmentation, and the appearance of a red rim around it. Treatment involves prompt surgical intervention, based on early diagnosis, and the use of radiotherapy and drugs to retard the growth and reproduction of the cells.

I. IA. SHAKHTMEISTER

melanoma

[mel·ə′nō·mə]
(medicine)
A malignant tumor composed of anaplastic melanocytes.
A benign or malignant tumor composed of melanocytes.

melanoma

Pathol a malignant tumour composed of melanocytes, occurring esp in the skin, often as a result of excessive exposure to sunlight
References in periodicals archive ?
According to the recommendation by the Western Society of Teachers of Oral Pathology (WESTOP) Banff Workshop, oral malignant melanomas should be considered separately from skin melanomas and sub-classified according to the histopathologic picture as in situ melanomas; invasive melanomas; combined: invasive melanomas with in situ components; and atypical melanocyte proliferation, in cases where there is an equivocal histologic diagnosis (16).
The invasive melanomas had a slightly higher percentage of peripheral-only pink (21/126 = 16.7%) compared to the in situ melanomas (22/170 = 12.9%).
By definition, all in situ melanomas have only radial growth phase.

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