Morrisey collaborated on a recent study led by Peranteau and Kiran Musunuru, MD, PhD, an associate professor of Cardiovascular Medicine at Penn, demonstrating the feasibility of
in utero gene editing to rescue a lethal metabolic liver disease in a mouse model -- the first time
in utero CRISPR-mediated gene editing prevented a lethal metabolic disorder in animals.
To this end, many groups have investigated the potential of
in utero gene transfer or
in utero gene correction as a potential method to treat monogenic myopathies.
Effects of
in Utero BaP Exposure on Reproductive Health
NAS diagnosis results from proof of
in utero exposure and the presence of clinical withdrawal symptoms in the baby.
In a multivariate analysis adjusted for
in utero drug exposures, the association between ADHD and maternal SLE was no longer significant.
The result was Golden Jubilee Stakes winner Art Connoisseur, sold
in utero along with his dam to agent Peter Doyle at the 2005 Tattersalls December sales.
In the bivariate analysis, blood lead levels,
in utero tobacco smoke, and serum cotinine were all significantly associated with ADHD.
Concerns about the adverse effects of maternal cocaine use during pregnancy on children exposed
in utero have been the focus of many studies since the 1980s, when cocaine use began to increase, first among more affluent socioeconomic groups, then shifting to lower-income groups with the advent of cheap crack cocaine.
With millions of pregnant women on the job these days, the issue of
in utero injuries has implications for employers and their liability insurance coverage.
(1.) Titus-Ernstoff L et al., Menstrual and reproductive characteristics of women whose mothers were exposed
in utero to diethylstilbestrol (DES), International Journal of Epidemiology, 2006, 35(4):862-868.
Picked on by upper classmen, unnoticed by the girl of his dreams, and further distressed by his mother's unexpected pregnancy, he struggles to tough out the year, and records his experiences in a journal addressed to the unwelcome little brother
in utero. By the end of school his fortunes have improved significantly.