inactivated vaccine


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inactivated vaccine

[in¦ak·tə‚vād·əd vak‚sēn]
(immunology)
References in periodicals archive ?
Current influenza vaccination program uses either attenuated vaccines or inactivated vaccines to induce protective immunity.
Specifically as for children aged 2-17 years old, the risk of influenza was not significantly lower among those who received the quadrivalent live attenuated influenza vaccine than among those who received no vaccine; the inactivated vaccine had a marked benefit over no vaccine (vaccine effectiveness, 60%; 95% CI, 47-70; P less than .001).
As shown in Figure 3, the VP1 protein, the VP1-gp120 and VP1-E2 recombinant fusion proteins, and the inactivated vaccine all effectively induced specific anti-FMDV serotype A IgG antibodies, and significant increases in serum IgG antibody levels were observed over time after the initial immunization in all groups except the PBS negative control group.
We found that our vaccine delivered protection at least as effectively as BCG, but without any biological risk, since it's an inactivated vaccine and thus cannot evolve into potentially virulent forms, as the live vaccines such as BCG could have the potential to do."
The high-dose trivalent inactivated vaccine, IIV3-HD (Fluzone High Dose), was licensed for use in the United States in 2009, with a requirement to show clinical benefits.
Immunization with this influenza nanoparticle vaccine elicited hemagglutination inhibition antibody titres more than tenfold higher than those from the licensed inactivated vaccine. Furthermore, it elicited neutralizing antibodies to two highly conserved vulnerable hemagglutinin structures that are targets of universal vaccines, the stem and the receptor binding site on the head.
They considered seizures that occurred with 24 hours after receiving an inactivated vaccine or five to twelve days after receiving a live attenuated vaccine.
Development and evaluation of an inactivated vaccine in oily adjuvant against Newcastle disease.
Overall, the most widely used seasonal flu vaccine, known as trivalent inactivated vaccine (TIV), was only 59% effective in healthy adults.
Systemic and local IgG1 and IgG2 anti-BoHV-1 antibody responses induced by the administration of an experimental inactivated vaccine were well characterized in the current investigation, but the functions of different antibody isotypes in cattle, relative to the specific mechanisms of protection against BoHV-1, need further investigation.