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inclusion-cell disease[iŋ′klü·zhən ‚sel ‚diz‚ēz]
A rare genetic disorder in which lysosomal hydrolases are transported out of the cell into the blood, rather than into the lysosome, resulting in the accumulation of undigested macromolecules within the lysosome. Abbreviated I-cell disease.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.