proband

(redirected from index case)
Also found in: Dictionary, Thesaurus, Medical, Legal, Financial, Wikipedia.
Related to index case: index patient, primary case

proband

[′prō‚band]
(genetics)
The clinically affected individual through whom a family is found that can be used to study the genetics of a particular disorder. Also known as propositius.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
Mentioned in ?
References in periodicals archive ?
The index cases were in contact with or resided on a farm where camels were kept.
Liquid TB culture samples from the index case and the presumed source case were retrieved from the National Health Laboratory Service at Tygerberg Hospital and Green Point TB laboratories, respectively, for comparison.
We created the variable time (in days) using the symptom onset date from the index case as the baseline date across the 810 case localities; that is, time ([X.sub.i], [Y.sub.i]).
Children exposed to index cases with TB, particularly sputum smear-positive pulmonary TB (PTB), are at risk of infection and when infected, infants and young children (<5 years old) are at high risk of developing the disease [2,3].
In this study, we screened pediatric and adult family members of index cases with brucellosis to detect unrecognized infected family members.
Household contacts: The individuals living in the same household or spending together many hours a day with the index case in the same living shelter.
In women with a single index case of HDP, the mortality rate compared to women with no HDP was threefold higher for diabetes, twofold higher for ischemic heart disease, and 85% higher for stroke.
In the index case, medication was contnued during the course of behavior therapy for management of depressive symptoms and for the anxiety related to the choking phobia.
Among 15 Ebola outbreaks in remote areas of nine counties with index case symptom onset dates during July 16--November 20, 2014, 12 investigations had complete data (Figure 1).
The two patients released from the Paynesville ETU are the father and younger brother of the presumed index case, a 15-year-old boy named Nathan Gbotoe from a suburb of the capital Monrovia who died from the disease last week.
Patients that were not inhabitants of Denmark at the index case or had migrated less than five years prior were also excluded, as were cases with chronic pancreatitis, pancreatic cancer, or polycystic ovary syndrome.
An index case is defined as a previously diagnosed leprosy patient living in the same house and sharing the same kitchen (intra-familial), or is within the social circle of the newly diagnosed leprosy patient.