Role of uremic toxin indoxyl
sulfate in the progression of cardiovascular disease.
The production of p-cresol sulfate and indoxyl
sulfate in vegetarians versus omnivores.
Indolecarboxylic acid ester [right arrow] Indoxyl
Enzymaticdegradation of urinary indoxyl
sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome.
Key Words: Nephrostomy tube, purple urine, PUBS, long-term indwelling catheter, alkaline urine, indoxyl
Indole was absorbed into the portal circulation and conjugates with SO [sub]4 to form indoxyl
In presence of a sulphatase producing organism, the urinary bacteria break down the indoxyl
sulphate to indoxyl
via sulphatase enzyme.
Renal medicine, pathophysiology, nephrology, and other researchers from Europe, the US, and Japan cover the definition, classification, listing, and mass spectrometric analysis of uremic toxins; selected toxins, including indoxyl
sulfate, asymmetric dimethylarginine, parathyroid hormone, and advanced glycation endproducts, and their chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods; and the therapeutic removal of toxins through hemodialysis, peritoneal dialysis, and oral sorbents.
Alleviation of cisplatin-induced acute kidney injury using phytochemical polyphenols is accompanied by reduced accumulation of indoxyl
sulfate in rats.
Urinary tract infection (uti) with bacteria possessing indoxyl
phosphatase and sulphatase enzymes, commonhyprovidencia stuarttiand rettgeri, pseudomonas auruginosa, proteus mirabilis, escherichia coli, klebsiella pneumoniae,morganella, citrobacter species, group b streptococci and enterococci (8, 13).
La reaccion en cadena responsable para el PUBS comienza con el triptofano de los alimentos que es metabolizado a indol en el intestino, luego es absorbido, pasa a la circulacion portal y convertido a sulfato de indoxyl
en el higado y excretado en la orina.
Some HPLC peaks were identified, such as creatinine, uric acid (the highest contribution), hypoxanthine, indoxyl
sulphate and hippuric acid.