inducible enzyme


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Related to inducible enzyme: Lac operon, constitutive enzyme, repressible enzyme

inducible enzyme

[in′dü·sə·bəl ′en‚zīm]
(biochemistry)
An enzyme which is present in trace quantities within a cell but whose concentration increases dramatically in the presence of substrate molecules.
References in periodicals archive ?
COX-2 is an inducible enzyme in the conversion of arachidonic acid to inflammatory prostaglandins, which is usually absent or minimally present at baseline in most normal tissues but is highly induced in response to inflammatory stimuli [25].
Activation of NF-[kappa]B up-regulates the expression of genes encoding adhesion molecules (E-selectin, ICAM, VCAM), pro-inflammatory cytokines (TNF-[alpha], IL-1, IL-2, IL-6, etc.), inducible enzymes (COX-2 and iNOS), some acute phase proteins, and immune receptors, all of which play critical roles in controlling inflammatory processes (Nam, 2006; Vanninietai.
The results suggest that [alpha]-amylase was an inducible enzyme and generally induced in the presence of carbon sources (Fig.
It is therefore plausible to suggest that the benzoquinone moiety of atrovirinone acts as an intracellular antioxidant leading to inhibition of NF-[kappa]B pathway activation and subsequent suppression of inducible enzyme genes.
[sup][6],[7] Cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS) are key enzymes in inflammation and oxidative stress, both of which are inducible enzymes and can be induced to mediate pathological damages.
The major factor for the expression of lipase activity has always been reported as the carbon source, since lipases are inducible enzymes (Gupta et al., 2004).