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Related to infiltrative: infiltrative cardiomyopathy


1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia



an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.


References in periodicals archive ?
These glands show an infiltrative architecture and nuclear atypia including hyperchromatic nuclei and few prominent nucleoli, similar to that seen in typical PCa.
Advanced imaging techniques (computed tomography, magnetic resonance imaging) are useful to evaluate the infiltrative distribution of the mass, the osteolytic changes of long bones, and possible pulmonary or intracoelomic metastases.
He also finds the drug helpful for infiltrative BCCs in cosmetically vulnerable areas and for edge persistence after Mohs surgery.
It is believed that BOOP is the source of 20 percent to 30 percent of all cases of chronic infiltrative lung disease.
Diffuse Infiltrative lymphocytosis syndrome (DILS) typically affects viscera (salivary glands and lungs being the most common sites), but can also involve peripheral blood, LN and mucosal sites.
His heart had a large fibrous nodular mass in the mitral valve cusp; there were numerous small, infiltrative, white, cheese-like lesions proximal to the aortic valve cusp and extending to the myocardium, and extensive fibrous thickening of the tricuspid valve cusp (Figs 1 and 2).
Birnbaum ordered a gastrointestinal series and an abdominal ultrasound, which revealed a two centimeter mass in the patient's stomach Subsequent medical procedures confirmed the presence of infiltrative gastric adenoid carcinoma, signet ring cell type.
There have been rare reports of acute diffuse infiltrative pulmonary disease of unknown etiology such as pneumonitis, interstitial pneumonia, lung infiltration and Acute Respiratory Distress Syndrome in patients receiving VELCADE.
Other organ involvement includes the heart (with infiltrative cardiomyopathy and conduction abnormalities), nervous system (with unilateral facial nerve palsy), and reticuloendothelial system (liver and spleen).
A chest X-ray showed infiltrative shadows in both lung fields compatible with pulmonary oedema.
Causes of headache include cerebral venous occlusion, Lyme disease, infiltrative disease, exposure to toxins, AIDS, and opportunistic meningitis.