To our knowledge, whereas Cd(II) has been shown to inhibit
a number of DNA repair enzymes, our studies are the first to identify a specific DNA repair protein target for lead.
Lab tests have demonstrated that AgION's technology is used effectively against a wide range of bacteria and fungi and naturally inhibits
microbial growth in food contact applications.
Cellular stress inhibits
vascular smooth muscle relaxation.
Further tests showed that acetaminophen inhibits
this same variant, linking the drug to the prostaglandin-making pathway.
OTCBB:FMVR), announced today that preclinical studies show that its compound for shingles inhibits
viral infections exceptionally quickly and that when FV-100 is dosed orally, the active compound shows good dose dependent pharmacokinetics.
Paul Talalay and his coworkers at Johns Hopkins Medical Institutions in Baltimore surprised cancer researchers in 1992 when they isolated sulforaphane, a compound in broccoli and its botanical kin that inhibits
the development of cancer (SN: 3/21/92, p.
Data presented at AACR demonstrate that compounds from ARIAD's kinase inhibitor program potently inhibit
a particular Bcr-Abl mutant called T315I.
They bind and apparently inhibit
apoptosis-induced proteases, enzymes that chop up other proteins.
The liver cancer study, entitled "Telomerase Antagonists GRN163 and GRN163L Inhibit
Tumor Growth and Increase Chemosensitivity of Human Hepatoma," was authored by researchers at Geron and at the Medical School Hannover in Germany, and appears in the current online publication of the journal Hepatology.
SAN DIEGO -- Ambit Biosciences today announced that a study utilizing its novel kinase profiling technology revealed several existing clinical drug candidates that bind to and inhibit
various mutations responsible for the development of resistance to the leading targeted cancer drugs Gleevec(R), IRESSA(R) and TARCEVA(TM).
Rene Rijnbrand of the University of Texas Medical Branch (UTMB) in Galveston will discuss how NEUGENE antisense drugs inhibit
this virus, which is known to cause a large percentage of the incidences of the common cold.
Thalidomide's ability to inhibit
angiogenesis appears unrelated to its effects on the immune system, they assert.