insulinase


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insulinase

[′in·sə·lə‚nās]
(biochemistry)
An enzyme produced by the liver which is able to inactivate insulin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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For instance, benzoic acid-related molecules inhibit insulinase and enhance insulin effects (Aybar et al., 2001).
A novel steroid from Elephantopus scaber L. an ethnomedicinal plant with antidiabetic activity
Hemolyzed samples contain an insulin-degrading enzyme and should not be analyzed unless they can be handled at 4 [degrees]C within ~2-3 h or an insulinase inhibitor has been added in the blood collection tube to prevent insulin degradation.
Insulin immunoassays: fast approaching 50 years of existence and still calling for standardization
Almost all insulin secreted into the blood will be transported without binding to proteins; the plasma half-life is only about 6 minutes and thus will be cleaned of blood completely within 10 to 15 minutes, unless only part of insulin that binds to receptors on the target cell; the rest will be broken by insulinase enzymes, that much of it is in the liver, some in kidneys and muscles, and slightly less in other tissues.
Effects of 8 weeks of endurance training on the concentration of 6-IL, insulin in male rats

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