insulinoma

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insulinoma

[‚in·sə·lə′nō·mə]
(medicine)
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References in periodicals archive ?
Insulinomas are functional pancreatic NETs which secrete endogenous insulin autonomously, regardless of blood glucose levels, resulting in a state of hyperinsulinemia [7].
En 1954 Wermer describio una familia con sindrome MEN-1 que se asocia con insulinomas y gastrinomas.
Using MIN6N8 cells, which are SV40 transformed insulinoma cells derived from NDO mice, Kim et al.
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.
Mas del 90% de los insulinomas son tumores pequenos y unicos; aproximadamente 10% son multiples, menos del 10% son malignos (clasicamente determinada por la evidencia de invasion local o metastasis) y del 5% al 10% estan asociados con la neoplasia endocrina multiple tipo 1 (NEM--1) (4-6) o sindrome de Wermer, desorden autosomico dominante asociado con mutaciones del gen NEM--1 (brazo largo del cromosoma 11q13), caracterizada por hiperplasia tiroidea, adenomas de la pituitaria anterior y tumores del pancreas endocrino y duodeno (7).
Both patients underwent surgery for suspected neuroendocrine tumors, the first for a suspected non-secreting neuroendocrine tumor and the second for a suspected insulinoma of the pancreatic body.
7 August 2014 - A study, carried out by Chinese researchers and published today in BMC Endocrine Disorders, has demonstrated that Chromogranin A (CgA) is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumours (PNETs) but not for insulinomas.
Most of the insulinomas are intrapancreatic, benign, and solitary (1), therefore, they have an excellent prognosis after surgical resection (1).
A hipoglicemia associada a neoplasia e descrita em caes nos casos de insulinomas, tumores hepaticos e raramente em outras formas neoplasicas decorrente provavelmente, do grande consumo de glicose pelo tumor (3, 6), o que levou a suspeita de insulinoma, e tambem pela ocorrencia da triade de Whippie, na qual ocorrem sinais neurologicos de correntes da hipoglicemia, concentracao glicemica em jejum abaixo de 40mg/dl e o alivio dos sintomas com administracao parenteral de glicose (7) condizendo com o caso descrito em que o paciente possuia crises convulsivas.
Pancreatic venous sampling and arteriography in localizing insulinomas and gastrinomas: procedure and results in 55 cases.
Pancreatic islet cell tumors include insulinomas, glucagonomas and gastrinomas and current treatment options are limited.