intercalated disc

(redirected from Intercalated disks)
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intercalated disc

[in′tər·kə‚lād·əd ′disk]
(histology)
A dense region at the junction of cellular units in cardiac muscle.
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References in periodicals archive ?
Currently, 16 mutations have been described in ARVC (Table 1), six of them being associated with desmosomal-type junctional complexes from the intercalated disks [11, 26, 27].
Another plausible hypothesis is that local proinflammatory mediators may interfere with the integrity and desmosomal activity of the intercalated disks, considering their ability of plakoglobin redistribution or TGF[beta]3 overexpression [36, 37].
The intercalated disks are irregular and wider than the normal cross-striations, and represent specialized junctions between cardiac muscle fibers (Fig.