interferon-gamma

(redirected from Interferon gamma-1b)
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Related to Interferon gamma-1b: Actimmune

interferon-gamma

[‚in·tər¦fir‚än ′gam·ə]
(immunology)
An interferon produced by T lymphocytes and large granular lymphocytes in response to foreign macromolecules.
References in periodicals archive ?
In the terms of an individual deal with an un-revealed third party, Horizon Pharma likewise licensed the U.S., European and Canadian intellectual property rights for interferon gamma-1b for the cure of Friedreich's ataxia.
Under the agreement, InterMune will fund and manage clinical and regulatory development of interferon gamma-1b for all indications.
Horizon Pharma plc, a biopharmaceutical company focused on improving patients' lives by identifying, developing, acquiring and commercializing differentiated and accessible medicines that address unmet medical needs, today announced that it, in collaboration with Fox Chase Cancer Center Temple Health, has initiated a Phase 1 clinical study to evaluate ACTIMMUNE (interferon gamma-1b) in combination with nivolumab in advanced solid tumors.
Leading the hepatology portfolio is the DIRECT trial, an ongoing Phase III study of daily interferon alfacon-1 (Infergen) plus ribavirin, and an ongoing Phase II trial of daily interferon alfacon-1 plus interferon gamma-1b (Actimmune) with and without ribavirin.
Interferon beta-1a (Avonex) and interferon beta-1b (Betaseron) are approved for treating multiple sclerosis; interferon gamma-1b (Actimmune) is used to reduce the frequency and severity of serious infections associated with chronic granulomatous disease and to delay the progression of malignant osteopetrosis.
InterMune (Nasdaq: ITMN), Burlingame, Calif., has filed a New Drug Submission (NDS) with the Therapeutic Products Programme of Health Canada (TPP) to market ACTIMMUNE(R) (Interferon gamma-1b) in Canada for chronic granulomatous disease (CGD) and severe, malignant osteopetrosis, both life-threatening childhood diseases.
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