interferon-gamma


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interferon-gamma

[‚in·tər¦fir‚än ′gam·ə]
(immunology)
An interferon produced by T lymphocytes and large granular lymphocytes in response to foreign macromolecules.
References in periodicals archive ?
Time interval to conversion of interferon-gamma release assay after exposure to tuberculosis.
Feasibility, acceptability, and cost of tuberculosis testing by whole--blood interferon-gamma assay.
Interferon-gamma release assays (IGRAs) are blood tests that determine whether a person has TB infection.
BPA-treated lupus-prone animals also produced less interferon-gamma than is normal for their strain.
Laboratory data indicates that PROCHYMAL is able to down-regulate the production of pro-inflammatory cytokines, including tumor necrosis factor-alpha or TNF-alpha and interferon-gamma.
Down-regulation of Bgp1(a) viral receptor by interferon-gamma is related to the antiviral state and resistance to mouse hepatitis virus 3 infection.
In psoriasis, these cells overproduce a damaging protein called interferon-gamma.
NF-kappaB is a well-known transcription regulator that controls the production of inflammatory cytokines such as TNF-alpha and Interferon-gamma.
When the scientists examined the chemistry of the animals' synovial fluid, they found that the untreated but not the treated mice show an excess of interferon-gamma.
In a concurrent study, the investigators showed that death of islets resulting from exposure to IL-1beta and interferon-gamma was also significantly reduced, meaning more viable islets remained.
Leptin encouraged helper T cells to make a socalled Th1 response, marked by secretion of chemicals such as interleukin-2 and interferon-gamma, rather than a Th2 response, which releases other interleukins.
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