interleukin-11


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Related to interleukin-11: IL-13, Oprelvekin, IL-3, Interleukin 12, Neumega

interleukin-11

[‚in·tər¦lük·ən i′lev·ən]
(immunology)
A pleiotropic cytokine produced by bone marrow-derived fibroblasts which supports the growth of certain cell types, such as B cells, neutrophils, and platelet-producing megakaryocytes. Abbreviated IL-11.
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References in periodicals archive ?
Yuda et al., "Mechanical induction of interleukin-11 regulates osteoblastic/cementoblastic differentiation of human periodontal ligament stem/ progenitor cells," Journal of Periodontal Research, vol.
Robak, "Relationship between circulating interleukin-10 (IL-10) with interleukin-6 (IL-6) type cytokines (IL-6, interleukin-11 (IL11), oncostatin M (OSM)) and soluble interleukin-6 (IL-6) receptor (sIL-6R) in patients with multiple myeloma," European Cytokine Network, vol.
Rizzoli, "The RANK/ RANK ligand system is involved in interleukin-6 and interleukin-11 up-regulation by human myeloma cells in the bone marrow microenvironment," Haematologica, vol.
A nucleotide variant in the promoter region of the interleukin-11 gene associated with decreased bone mineral density.
Association of interleukin-11 promoter variant with bone mineral density in pre-menopausal women.
The cellular actions of interleukin-11 on bone resorption in vitro.
Production of interleukin-11 in bone-derived endothelial cells and its role in the formation of osteolytic bone metastasis.
bedrosin, AJ.dorner, Defining the mechanism of action of interleukin-11 on the progression of radiation-induced mucositis in hamsters.
Dorner, "Interleukin-11: a gp130 cytokine," Annals of the New York Academy of Sciences, vol.
Trepicchio, "Interleukin-11 modulates Th1/Th2 cytokine production from activated [CD4.sup.+] T cells," Journal of Interferon and Cytokine Research, vol.