intermediate filament


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intermediate filament

[‚int·ər′mēd·ē·ət ′fil·ə·mənt]
(cell and molecular biology)
Any of several classes of cell-specific cytoplasmic filaments of 8-12 nanometers in diameter; protein composition varies from one cell type to another.
References in periodicals archive ?
Mspl RFLP in the gene for a Type I intermediate filament wool keratin.
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.
Prahlad et al., "A high molecular weight intermediate filament-associated protein in BHK-21 cells is nestin, a type VI intermediate filament protein," The Journal of Biological Chemistry, vol.
Peripherin, a new member of the intermediate filament protein family.
Figure 12: infectious muscle 1 hour after injection, Desmin intermediate filament (arrowhead) within the Myocytes that surrounding by inflammatory cells (arrow) is seen.
As such, dystrophin constitutes a major scaffolding protein of normal muscle which links cytoskeletal actin, microtubules and intermediate filaments to the extracellular matrix.
Coulombe, "Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm," Genes and Development, vol.
In all stages studied, a redundancy of intermediate filaments was typical for the Purkinje fibers.
Intermediate filament expression in mesotheliomas: Leimyoid mesotheliomas are not uncommon.
Keratins are defined as intermediate filament forming proteins with specific physicochemical properties produced in any vertebrate epithelia.
This wide expression and distribution of vimentin, an intermediate filament that can sustain extremely large cellular deformations, will provide stability to the HNS cells submitted to regular morphological adaptations caused by a seasonal severe arid biotope.

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